Evidence map›Paper›PMID 20803232›Full record

ReviewCellular and molecular life sciences : CMLS2011

The ING family tumor suppressors: from structure to function.

Almass-Houd Aguissa-Touré, Ronald P C Wong, Gang Li

Abstract readReview
In one paragraph

Review in Cellular and molecular life sciences : CMLS, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Photoperiod-driven gene regulation in the brain ofFrontiers in endocrinology · 2026
    Article
  2. Article
  3. Article
  4. SCFEMBO reports · 2021
    Article
  5. Article
  6. Review
  7. The expression levels of the sirtuins in patients with BCC.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2016
    Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Almass-Houd Aguissa-TouréDepartment of Dermatology and Skin Science, Jack Bell Research Centre, Vancouver Coastal Health Research Institute, University of British Columbia, 2660 Oak Street, Vancouver, BC V6H 3Z6, Canada.
Ronald P C Wong
Gang Li

Funding

Canadian Institutes of Health Research MOP-84559Canadian Institutes of Health Research MOP-93810
6 · The paper itself

Abstract

The Inhibitor of Growth (ING) proteins belong to a well-conserved family which presents in diverse organisms with several structural and functional domains for each protein. The ING family members are found in association with many cellular processes. Thus, the ING family proteins are involved in regulation of gene transcription, DNA repair, tumorigenesis, apoptosis, cellular senescence and cell cycle arrest. The ING proteins have multiple domains that are potentially capable of binding to many partners. It is conceivable, therefore, that such proteins could function similarly within protein complexes. In this case, within this family, each function could be attributed to a specific domain. However, the role of ING domains is not definitively clear. In this review, we summarize recent advances in structure-function relationships in ING proteins. For each domain, we describe the known biological functions and the approaches utilized to identify the functions associated with ING proteins.

Indexed as

Amino Acid MotifsChromatin Assembly and DisassemblyHomeodomain ProteinsMultigene FamilyNuclear Localization SignalsProtein Structure, TertiaryStructure-Activity RelationshipTranscription, GeneticTumor Suppressor ProteinsHomeodomain ProteinsNuclear Localization SignalsTumor Suppressor Proteins

Identifiers

PMID20803232
PMCPMC11114739

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.