Evidence map›Paper›PMID 20803230›Full record

ReviewCellular and molecular life sciences : CMLS2011

Spotlight on post-transcriptional control in the circadian system.

Dorothee Staiger, Tino Köster

Abstract readReview
In one paragraph

Review in Cellular and molecular life sciences : CMLS, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Article
  2. Article
  3. Regulation of theG3 (Bethesda, Md.) · 2019
    Article
  4. Article
  5. Circadian Posttranscriptional Regulatory Mechanisms in Mammals.Cold Spring Harbor perspectives in biology · 2018
    Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. The circadian clock goes genomic.Genome biology · 2013
    Review
  13. Ribonucleoprotein complexes that control circadian clocks.International journal of molecular sciences · 2013
    Review
  14. Article
  15. Circadian clocks and metabolism.Handbook of experimental pharmacology · 2013
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Dorothee StaigerMolecular Cell Physiology, Bielefeld University, 33501, Bielefeld, Germany. dorothee.staiger@uni-bielefeld.de
Tino Köster

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An endogenous timing mechanism, the circadian clock, causes rhythmic expression of a considerable fraction of the genome of most organisms to optimally align physiology and behavior with their environment. Circadian clocks are self-sustained oscillators primarily based on transcriptional feedback loops and post-translational modification of clock proteins. It is increasingly becoming clear that regulation at the RNA level strongly impacts the cellular circadian transcriptome and proteome as well as the oscillator mechanism itself. This review focuses on posttranscriptional events, discussing RNA-binding proteins that, by influencing the timing of pre-mRNA splicing, polyadenylation and RNA decay, shape rhythmic expression profiles. Furthermore, recent findings on the contribution of microRNAs to orchestrating circadian rhythms are summarized.

Indexed as

Circadian ClocksModels, GeneticRNA Processing, Post-TranscriptionalAnimalsArabidopsisChlamydomonasDrosophilaMammalsMicroRNAsNeurosporaPolyadenylationProtein BiosynthesisRNA, AntisenseRNA, MessengerRNA SplicingRNA StabilityMicroRNAsRNA, AntisenseRNA, Messenger

Identifiers

PMID20803230
PMCPMC11114774

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.