ArticleNano today2010
PROTEIN TEMPLATES IN HARD TISSUE ENGINEERING.
Article in Nano today, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Paramagnetic Functionalization of Biocompatible Scaffolds for Biomedical Applications: A Perspective.Bioengineering (Basel, Switzerland) · 2020Review
- Article
- The Significance and Utilisation of Biomimetic and Bioinspired Strategies in the Field of Biomedical Material Engineering: The Case of Calcium Phosphat-Protein Template Constructs.Materials (Basel, Switzerland) · 2020Review
- A salt-based method to adapt stiffness and biodegradability of porous collagen scaffolds.RSC advances · 2019Article
- Nanoengineered implant as a new platform for regenerative nanomedicine using 3D well-organized human cell spheroids.International journal of nanomedicine · 2017Article
- Biological and MRI characterization of biomimetic ECM scaffolds for cartilage tissue regeneration.Biomaterials · 2015Article
- Biomimetic extracellular matrix mediated somatic stem cell differentiation: applications in dental pulp tissue regeneration.Frontiers in physiology · 2015Review
- Biomimetically enhanced demineralized bone matrix for bone regenerative applications.Frontiers in physiology · 2015Article
- Dentin Matrix Proteins in Bone Tissue Engineering.Advances in experimental medicine and biology · 2015Review
- Synthesis of carboxylic block copolymers via reversible addition fragmentation transfer polymerization for tooth erosion prevention.Journal of dental research · 2014Article
- 3-D self-assembling leucine zipper hydrogel with tunable properties for tissue engineering.Biomaterials · 2014Article
- Biomimetic remineralization of dentin.Dental materials : official publication of the Academy of Dental Materials · 2014Article
- Odontogenic induction of dental stem cells by extracellular matrix-inspired three-dimensional scaffold.Tissue engineering. Part A · 2014Article
- Flagellar display of bone-protein-derived peptides for studying peptide-mediated biomineralization.Langmuir : the ACS journal of surfaces and colloids · 2012Article
- Biomimetic extracellular matrix-incorporated scaffold induces osteogenic gene expression in human marrow stromal cells.Tissue engineering. Part A · 2012Article
- Natural and Genetically Engineered Proteins for Tissue Engineering.Progress in polymer science · 2012Article
- In situ AFM study of amelogenin assembly and disassembly dynamics on charged surfaces provides insights on matrix protein self-assembly.Journal of the American Chemical Society · 2011Article
- Inorganic-Organic Nanocomposite Assembly Using Collagen as Template and Sodium Tripolyphosphate as A Biomimetic Analog of Matrix Phosphoprotein.Crystal growth & design · 2011Article
- Intrafibrillar collagen mineralization produced by biomimetic hierarchical nanoapatite assembly.Advanced materials (Deerfield Beach, Fla.) · 2011Article
- Material binding peptides for nanotechnology.Molecules (Basel, Switzerland) · 2011Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Biomineralization processes such as formation of bones and teeth require controlled mineral deposition and self-assembly into hierarchical biocomposites with unique mechanical properties. Ideal biomaterials for regeneration and repair of hard tissues must be biocompatible, possess micro and macroporosity for vascular invasion, provide surface chemistry and texture that facilitate cell attachment, proliferation, differentiation of lineage specific progenitor cells, and induce deposition of calcium phosphate mineral. To expect in-vivo like cellular response several investigators have used extracellular matrix proteins as templates to recreate in-vivo microenvironment for regeneration of hard tissues. Recently, several novel methods of designing tissue repair and restoration materials using bioinspired strategies are currently being formulated. Nanoscale structured materials can be fabricated via the spontaneous organization of self-assembling proteins to construct hierarchically organized nanomaterials. The advantage of such a method is that polypeptides can be specifically designed as building blocks incorporated with molecular recognition features and spatially distributed bioactive ligands that would provide a physiological environment for cells in-vitro and in-vivo. This is a rapidly evolving area and provides a promising platform for future development of nanostructured templates for hard tissue engineering. In this review we try to highlight the importance of proteins as templates for regeneration and repair of hard tissues as well as the potential of peptide based nanomaterials for regenerative therapies.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.