ArticleThe open neurology journal2010
Animal models of ischemic stroke. Part one: modeling risk factors.
Article in The open neurology journal, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- A Review on Preclinical Models of Ischemic Stroke: Insights Into the Pathomechanisms and New Treatment Strategies.Current neuropharmacology · 2022Review
- Characterizing and Profiling microRNAs in Dogs Undergoing Induced Ischemic Brain Stroke After Middle Cerebral Artery Occlusion Under Fluoroscopic Guidance.Vascular health and risk management · 2021Article
- Medium- and long-term functional behavior evaluations in an experimental focal ischemic stroke mouse model.Cognitive neurodynamics · 2020Article
- Dietary Anthocyanins and Stroke: A Review of Pharmacokinetic and Pharmacodynamic Studies.Nutrients · 2019Review
- Nonhuman primate models of focal cerebral ischemia.Neural regeneration research · 2017Review
- Inflammatory Disequilibrium in Stroke.Circulation research · 2016Review
- Human Motor Cortex Functional Changes in Acute Stroke: Gender Effects.Frontiers in neuroscience · 2016Article
- Canine model of ischemic stroke with permanent middle cerebral artery occlusion: clinical features, magnetic resonance imaging, histopathology, and immunohistochemistry.Journal of veterinary science · 2015Article
- Sex differences in stroke.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2012Review
- Recovery from ischemia in the middle-aged brain: a nonhuman primate model.Neurobiology of aging · 2012Article
- The immunology of stroke: from mechanisms to translation.Nature medicine · 2011Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ischemic stroke is one of the leading causes of long-term disability and death in developed and developing countries. As emerging disease, stroke related mortality and morbidity is going to step up in the next decades. This is both due to the poor identification of risk factors and persistence of unhealthy habits, as well as to the aging of the population. To counteract the estimated increase in stroke incidence, it is of primary importance to identify risk factors, study their effects, to promote primary and secondary prevention, and to extend the therapeutic repertoire that is currently limited to the very first hours after stroke. While epidemiologic studies in the human population are essential to identify emerging risk factors, adequate animal models represent a fundamental tool to dissect stroke risk factors to their molecular mechanism and to find efficacious therapeutic strategies for this complex multi- factorial disorder. The present review is organized into two parts: the first part deals with the animal models that have been developed to study stroke and its related risk factors and the second part analyzes the specific stroke models. These models represent an indispensable tool to investigate the mechanisms of cerebral injury and to develop novel therapies.
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