ArticleNature genetics2010
The genome of the domesticated apple (Malus × domestica Borkh.).
Article in Nature genetics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 822 papers.
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Who cites it
822 citing papers in PubMed, 2,125 citations in OpenAlex.
- Candidate genes with antagonistic roles in stomatal development are associated with population-wide variation in apple.Horticulture research · 2026Article
- Mechanism Underlying the Color Differences in Apples Based on Metabolomic and Transcriptomic Analyses.International journal of molecular sciences · 2026Article
- Genome-Wide Characterization of the Apple HD-Zip IV Gene Family and Functional Validation of MdHDZIV3 Under PEG-Induced Osmotic Stress.Plants (Basel, Switzerland) · 2026Article
- Genome-wide analysis of the HDAC gene family in Pyrus betulifolia and functional validation of PcHDAC5 and PcHDT1.2 in Pyrus calleryana seed dormancy release.Journal of plant research · 2026Article
- Article
- Assembly and annotation of the 'Golden Delicious' Doubled-Haploid GDDH18 apple genome.G3 (Bethesda, Md.) · 2026Article
- Compact Retention and Lineage-Specific Sequence Divergence of ALMT Genes in Acidophilic Vaccinium.Plants (Basel, Switzerland) · 2026Article
- Identifying the contributions of progenitor Malus species to cultivated apple (M. domestica) using 20K SNP array data.BMC genomics · 2026Article
- Cloning and functional determination of PpyASR1 during fruit development in Pyrus pyrifolia.BMC plant biology · 2026Article
- Genomic divergence, introgression and KASP fingerprinting panel development in five cultivar groups of sweet osmanthus.BMC plant biology · 2026Article
- Promoter variation affects binding affinity of the transcription factor MdWRKY20 to theHorticulture research · 2026Article
- Genome Assembly Revealed MdZAT5 Coordinates Anthocyanin Biosynthesis in Apple Fruit Peel and Flesh by Interacting With MdHY5.Plant biotechnology journal · 2026Article
- MdNF-YB14, an apple NF-Y transcription factor, acts as a positive regulator of drought tolerance.Plant cell reports · 2026Article
- Haplotype-resolved chromosome-level genome assemblies of nineteen apple (Malus domestica Borkh.) cultivars.Scientific data · 2026Article
- Natural variations in MdBPM2/MdRGLG3-MdNAC83 network controlling the quantitative segregation of apple fruit storability.Journal of integrative plant biology · 2026Article
- The PbrMADS1-PbrMYB169 complex has uniquely emerged to regulate lignification of stone cells in pear.Journal of integrative plant biology · 2026Article
- Genome-wide identification and characterization of theFrontiers in plant science · 2026Article
- Molecular monitoring and multiplex qPCR-based detection ofFrontiers in insect science · 2026Article
- Pharmacogenomics of treatment toxicities in pediatric B-Cell ALL: toward safer precision therapy.Frontiers in pharmacology · 2026Review
- Application of Genome-Assisted Prediction (GAP) for Apple Fruit Weight.Plants (Basel, Switzerland) · 2025Article
762 more citing papers are in PubMed but not listed here.
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86 authors at 15 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We report a high-quality draft genome sequence of the domesticated apple (Malus × domestica). We show that a relatively recent (>50 million years ago) genome-wide duplication (GWD) has resulted in the transition from nine ancestral chromosomes to 17 chromosomes in the Pyreae. Traces of older GWDs partly support the monophyly of the ancestral paleohexaploidy of eudicots. Phylogenetic reconstruction of Pyreae and the genus Malus, relative to major Rosaceae taxa, identified the progenitor of the cultivated apple as M. sieversii. Expansion of gene families reported to be involved in fruit development may explain formation of the pome, a Pyreae-specific false fruit that develops by proliferation of the basal part of the sepals, the receptacle. In apple, a subclade of MADS-box genes, normally involved in flower and fruit development, is expanded to include 15 members, as are other gene families involved in Rosaceae-specific metabolism, such as transport and assimilation of sorbitol.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.