ArticleApplied and environmental microbiology2010
Extracts of edible and medicinal plants damage membranes of Vibrio cholerae.
Article in Applied and environmental microbiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
72 citing papers in PubMed, 249 citations in OpenAlex.
- Medicinal Plants: A Promising Therapeutic Approach for Addressing Antimicrobial Resistance.International journal of molecular sciences · 2026Review
- High-Throughput Screening of FDA-Approved Drugs for Antibacterial and Antibiofilm Activities Against Multidrug-resistantACS omega · 2026Article
- Protective Role ofMicroorganisms · 2025Article
- Article
- Antimycobacterial and Antifungal Activities of Leaf Extracts FromScientifica · 2024Article
- Antibacterial action of slightly acidic electrolytic water againstFrontiers in microbiology · 2024Article
- Article
- Insights into the Mechanisms of Reuterin againstFoods (Basel, Switzerland) · 2023Article
- Antibacterial mechanism of vanillin againstHeliyon · 2023Article
- Chemical Composition ofAntibiotics (Basel, Switzerland) · 2023Article
- Transcriptome Analysis of Protocatechualdehyde againstFoods (Basel, Switzerland) · 2023Article
- Evaluation of the Effect ofPathogens (Basel, Switzerland) · 2023Article
- Phytochemical profiling, antimicrobial, and antioxidant activities of hydroethanolic extracts of prickly pear (Food science & nutrition · 2023Article
- Article
- Copper-Based Compounds against Erwinia amylovora: Response Parameter Analysis and Suppression of Fire Blight in Apple.The plant pathology journal · 2023Article
- Inhibitory mechanism of quercetin onFrontiers in microbiology · 2023Article
- The antibacterial mechanism of compound preservatives combined with low voltage electric fields on the preservation of steamed mussels (Frontiers in nutrition · 2023Article
- Antibacterial activity of guava, moringa, camphor bush and pelargonium extracts against bacterial wilt (Saudi journal of biological sciences · 2022Article
- Natural products as antivibrio agents: insight into the chemistry and biological activity.RSC advances · 2022Review
- Flavonoids from Sedum aizoon L. inhibit Botrytis cinerea by negatively affecting cell membrane lipid metabolism.Applied microbiology and biotechnology · 2022Article
12 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The use of natural compounds from plants can provide an alternative approach against food-borne pathogens. The mechanisms of action of most plant extracts with antimicrobial activity have been poorly studied. In this work, changes in membrane integrity, membrane potential, internal pH (pH(in)), and ATP synthesis were measured in Vibrio cholerae cells after exposure to extracts of edible and medicinal plants. A preliminary screen of methanolic, ethanolic, and aqueous extracts of medicinal and edible plants was performed. Minimal bactericidal concentrations (MBCs) were measured for extracts showing high antimicrobial activity. Our results indicate that methanolic extracts of basil (Ocimum basilicum L.), nopal cactus (Opuntia ficus-indica var. Villanueva L.), sweet acacia (Acacia farnesiana L.), and white sagebrush (Artemisia ludoviciana Nutt.) are the most active against V. cholera, with MBCs ranging from 0.5 to 3.0 mg/ml. Using four fluorogenic techniques, we studied the membrane integrity of V. cholerae cells after exposure to these four extracts. Extracts from these plants were able to disrupt the cell membranes of V. cholerae cells, causing increased membrane permeability, a clear decrease in cytoplasmic pH, cell membrane hyperpolarization, and a decrease in cellular ATP concentration in all strains tested. These four plant extracts could be studied as future alternatives to control V. cholerae contamination in foods and the diseases associated with this microorganism.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.