ReviewInternational review of cell and molecular biology2010
Axonal ensheathment and intercellular barrier formation in Drosophila.
Review in International review of cell and molecular biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed, 13 citations in OpenAlex.
- Feminization of the Blood-Brain Barrier Changes the Brain Transcriptome ofCurrent issues in molecular biology · 2025Article
- Pathogenesis of α-Synuclein in Parkinson's Disease: From a Neuron-Glia Crosstalk Perspective.International journal of molecular sciences · 2022Review
- Delta/Notch signaling in glia maintains motor nerve barrier function and synaptic transmission by controlling matrix metalloproteinase expression.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Clearing Your Mind: Mechanisms of Debris Clearance After Cell Death During Neural Development.Annual review of neuroscience · 2022Review
- Vitamin E Deficiency Disrupts Gene Expression Networks during Zebrafish Development.Nutrients · 2021Article
- Molecular Chaperone Calnexin Regulates the Function ofFrontiers in molecular neuroscience · 2017Article
- Changes in organelle position and epithelial architecture associated with loss of CrebA.Biology open · 2015Article
- Glial cells in neuronal development: recent advances and insights from Drosophila melanogaster.Neuroscience bulletin · 2014Review
- Article
- Sex-specific signaling in the blood-brain barrier is required for male courtship in Drosophila.PLoS genetics · 2013Article
- Review
- Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Glial cells are critical players in every major aspect of nervous system development, function, and disease. Other than their traditional supportive role, glial cells perform a variety of important functions such as myelination, synapse formation and plasticity, and establishment of blood-brain and blood-nerve barriers in the nervous system. Recent studies highlight the striking functional similarities between Drosophila and vertebrate glia. In both systems, glial cells play an essential role in neural ensheathment thereby isolating the nervous system and help to create a local ionic microenvironment for conduction of nerve impulses. Here, we review the anatomical aspects and the molecular players that underlie ensheathment during different stages of nervous system development in Drosophila and how these processes lead to the organization of neuroglial junctions. We also discuss some key aspects of the invertebrate axonal ensheathment and junctional organization with that of vertebrate myelination and axon-glial interactions. Finally, we highlight the importance of intercellular junctions in barrier formation in various cellular contexts in Drosophila. We speculate that unraveling the genetic and molecular mechanisms of ensheathment across species might provide key insights into human myelin-related disorders and help in designing therapeutic interventions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.