Evidence map›Paper›PMID 20801417›Full record

ReviewInternational review of cell and molecular biology2010

Use of virtual cell in studies of cellular dynamics.

Boris M Slepchenko, Leslie M Loew

Abstract readReview
In one paragraph

Review in International review of cell and molecular biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Mad dephosphorylation at the nuclear pore is essential for asymmetric stem cell division.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Computational analysis of Rho GTPase cycling.PLoS computational biology · 2013
    Article
  16. Spatial modeling of cell signaling networks.Methods in cell biology · 2012
    Article
  17. Modeling cellular processes in 3D.Trends in cell biology · 2011
    Review
  18. Article
  19. Developing models in virtual cell.Science signaling · 2011
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Boris M SlepchenkoRichard D. Berlin Center for Cell Analysis and Modeling, Department of Cell Biology, University of Connecticut Health Center, Farmington, Connecticut, USA.
Leslie M Loew

Funding

STRUCTUREU54GM064346 · NIGMS · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI IMPERIALI, BARBARA · 2001 to 2010
$74.9M
VIRTUAL FCSP41RR013186 · NCRR · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI LOEW, LESLIE M · 1998 to 2011
$14.2M
POLARITY IN NETWORKS AND PATHWAYS(RMI)U54RR022232 · NCRR · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI LOEW, LESLIE M · 2005 to 2009
$12.9M
TR&D4 Spatial Modeling: Modeling Framework for Cell MotilityP41GM103313 · NIGMS · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI LOEW, LESLIE M · 2012 to 2018
$9.7M
NCRR NIH HHS P41 RR013186NCRR NIH HHS P41-RR13186NCRR NIH HHS U54 RR022232NIGMS NIH HHS P41 GM103313NIGMS NIH HHS U54 GM064346
6 · The paper itself

Abstract

The Virtual Cell (VCell) is a unique computational environment for modeling and simulation of cell biology. It has been specifically designed to be a tool for a wide range of scientists, from experimental cell biologists to theoretical biophysicists. The models created with VCell can range from the simple, to evaluate hypotheses or to interpret experimental data, to complex multilayered models used to probe the predicted behavior of spatially resolved, highly nonlinear systems. In this chapter, we discuss modeling capabilities of VCell and demonstrate representative examples of the models published by the VCell users.

Indexed as

Cell Physiological PhenomenaComputer SimulationModels, BiologicalActive Transport, Cell NucleusCalciumSignal TransductionUser-Computer InterfaceCalcium

Identifiers

PMID20801417
PMCPMC3519358

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.