ArticleProgress in retinal and eye research2011
Ciliary blood flow and aqueous humor production.
Article in Progress in retinal and eye research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed, 103 citations in OpenAlex.
- Trial
- Monitoring outcomes of the first human whole eye allotransplant.Documenta ophthalmologica. Advances in ophthalmology · 2026Article
- CT Radiomic Features of the Crystalline Lens and Association with Age, Hypertension and Cerebral White Matter Lesions.Diagnostics (Basel, Switzerland) · 2026Article
- Symptomatic intraocular pressure dysregulation during clopidogrel exposure after patent foramen ovale closure in a patient with ocular hypertension and angle crowding: a Case Report.Frontiers in medicine · 2026Article
- Cyclocryotherapy applied at the 3 o'clock and 9 o'clock positions combined with anti-VEGF injections for advanced neovascular glaucoma.International ophthalmology · 2025Article
- The Effect of Sevoflurane Versus Total Intravenous Anesthesia on Intraocular Pressure in Patients Undergoing Coronary Artery Bypass Graft Surgery with Cardiopulmonary Bypass: A Prospective Observational Study.Medicina (Kaunas, Lithuania) · 2025Observational
- Trace Element Concentration in the Blood and Aqueous Humor of Subjects with Eye Cataract.Biological trace element research · 2025Article
- Reduced-Order Model for Cell Volume Homeostasis: Application to Aqueous Humor Production.Mathematical & computational applications · 2025Article
- Intraocular Pressure Equations Utilizing Aqueous Fluid Flow and Flow Facility in the Steady-State and Time-Dependent Domains.Clinical ophthalmology (Auckland, N.Z.) · 2025Article
- Enhanced Intrusion of Exogenous Airborne Fine Particles toward Eyes in Humans and Animals: Where Damaged Blood-Ocular Barrier Plays a Crucial Role.Environmental science & technology · 2024Article
- Targeting circular RNA-Glra2 alleviates retinal neurodegeneration induced by ocular hypertension.Aging · 2023Article
- Uveal vascular bed in health and disease: uveal vascular bed anatomy. Paper 1 of 2.Eye (London, England) · 2023Review
- Imaging ocular water inflow in the mouse with deuterium oxide MRI.Magnetic resonance imaging · 2023Article
- The role of conventional and unconventional adaptive routes in lowering of intraocular pressure: Theoretical model and simulation.Physics of fluids (Woodbury, N.Y. : 1994) · 2023Article
- Ocular manifestations of central insulin resistance.Neural regeneration research · 2023Article
- Mechanical Stretch Activates TRPV4 and Hemichannel Responses in the Nonpigmented Ciliary Epithelium.International journal of molecular sciences · 2023Article
- Simulation of gravity- and pump-driven perfusion techniques for measuring outflow facility of ex vivo and in vivo eyes.PloS one · 2023Article
- Noncoding RNAs Are Promising Therapeutic Targets for Diabetic Retinopathy: An Updated Review (2017-2022).Biomolecules · 2022Review
- A Mathematical Model of Aqueous Humor Production and Composition.Investigative ophthalmology & visual science · 2022Article
- Ocular Autonomic Nervous System: An Update from Anatomy to Physiological Functions.Vision (Basel, Switzerland) · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Aqueous humor production is a metabolically active process sustained by the delivery of oxygen and nutrients and removal of metabolic waste by the ciliary circulation. This article describes our investigations into the relationship between ciliary blood flow and aqueous humor production. The results presented indicate that there is a dynamic relationship between ciliary blood flow and aqueous humor production, with production being blood flow independent above a critical level of perfusion, and blood flow dependent below it. The results also show that the plateau portion of the relationship shifts up or down depending on the level of secretory stimulation or inhibition, and that oxygen is one critical factor provided by ciliary blood flow. Also presented is a theoretical model of ocular hydrodynamics incorporating these new findings.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.