ArticlePflugers Archiv : European journal of physiology1990
Characterization of butyrate-dependent electroneutral Na-Cl absorption in the rat distal colon.
Article in Pflugers Archiv : European journal of physiology, 1990. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 50 citations in OpenAlex.
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- Carbonic anhydrase influences asymmetric sodium and acetate transport across omasum of sheep.Animal bioscience · 2021Article
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- Oral rehydration therapy in the second decade of the twenty-first century.Current gastroenterology reports · 2014Review
- Enteric infections, diarrhea, and their impact on function and development.The Journal of clinical investigation · 2008Review
- Transport of acetate and sodium in sheep omasum: mutual, but asymmetric interactions.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2006Article
- Effects of butyrate on active sodium and chloride transport in rat and rabbit distal colon.The Journal of physiology · 2002Article
- Stimulation of sodium chloride absorption from secreting rat colon by short-chain fatty acids.Digestive diseases and sciences · 1999Article
- Article
- Apical membrane Cl-butyrate exchange: mechanism of short chain fatty acid stimulation of active chloride absorption in rat distal colon.The Journal of membrane biology · 1994Article
- Segmental differences in short-chain fatty acid transport in rabbit colon: effect of pH and Na.The Journal of membrane biology · 1993Article
- Article
- Effects of amiloride and ouabain on short-chain fatty acid transport in guinea-pig large intestine.The Journal of physiology · 1993Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Recent studies have established that mucosal butyrate stimulates electroneutral sodium-chloride (Na-Cl) absorption in the distal colon of the rat and a model in which Na-hydrogen (H) and Cl-butyrate exchanges are coupled has been proposed as the mechanism of butyrate-dependent electroneutral Na-Cl absorption. These studies were designed to examine butyrate-dependent electroneutral Na-Cl absorption in experimental conditions in which HCO3-dependent electroneutral Na-Cl absorption is inhibited: in Na-depleted (aldosterone-treated) animals and in the presence of increased mucosal cyclic adenosine monophosphate (AMP). Butyrate-dependent electroneutral Na-Cl absorption was markedly reduced in Na-depleted rats. In contrast, the inhibition of both net Na and net Cl absorption by 5 mM serosal theophylline was significantly less in butyrate-containing, HCO3-free Ringer solution than in butyrate-free- HCO3-containing Ringer solution. These studies indicate that cyclic AMP does not inhibit butyrate-dependent electroneutral Na-Cl absorption and we propose that the mechanism of cyclic AMP inhibition of HCO3-dependent electroneutral Na-Cl absorption may be a result of its inhibition of Cl-HCO3, not Na-H exchange.
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