ArticleJournal of biomedical optics
Toward guidance of epicardial cardiac radiofrequency ablation therapy using optical coherence tomography.
Article in Journal of biomedical optics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 34 citations in OpenAlex.
- Multimodal PSOCT-NIRS catheter for guided ablation of atrial fibrillation.Journal of biomedical optics · 2026Article
- Toward the development of a polarimetric tool to diagnose the fibrotic human ventricular myocardium.Journal of biomedical optics · 2022Article
- Polarization-sensitive optical coherence tomography monitoring of percutaneous radiofrequency ablation in left atrium of living swine.Scientific reports · 2021Article
- Feasibility of near-infrared spectroscopy as a tool for anatomical mapping of the human epicardium.Biomedical optics express · 2020Article
- Intracardiac radiofrequency ablation in living swine guided by polarization-sensitive optical coherence tomography.Journal of biomedical optics · 2020Article
- Steerable OCT catheter for real-time assistance during teleoperated endoscopic treatment of colorectal cancer.Biomedical optics express · 2020Article
- Optical coherence tomography imaging of cardiac substrates.Quantitative imaging in medicine and surgery · 2019Review
- Real-time optical spectroscopic monitoring of nonirrigated lesion progression within atrial and ventricular tissues.Journal of biophotonics · 2019Article
- Integrated RFA/PSOCT catheter for real-time guidance of cardiac radio-frequency ablation.Biomedical optics express · 2018Article
- Tissue-Specific Optical Mapping Models of Swine Atria Informed by Optical Coherence Tomography.Biophysical journal · 2018Article
- Anatomical and Optical Properties of Atrial Tissue: Search for a Suitable Animal Model.Cardiovascular engineering and technology · 2017Article
- Laser thermal therapy monitoring using complex differential variance in optical coherence tomography.Journal of biophotonics · 2017Article
- Automated classification of optical coherence tomography images of human atrial tissue.Journal of biomedical optics · 2016Article
- Near-infrared spectroscopy integrated catheter for characterization of myocardial tissues: preliminary demonstrations to radiofrequency ablation therapy for atrial fibrillation.Biomedical optics express · 2015Article
- Fiber-optic catheter-based polarization-sensitive OCT for radio-frequency ablation monitoring.Optics letters · 2014Article
- Miniature forward-imaging B-scan optical coherence tomography probe to guide real-time laser ablation.Lasers in surgery and medicine · 2014Article
- An automated 3D registration method for optical coherence tomography volumes.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2014Article
- Extracting three-dimensional orientation and tractography of myofibers using optical coherence tomography.Biomedical optics express · 2013Article
- Use of endogenous NADH fluorescence for real-time in situ visualization of epicardial radiofrequency ablation lesions and gaps.American journal of physiology. Heart and circulatory physiology · 2012Article
- A forward-imaging needle-type OCT probe for image guided stereotactic procedures.Optics express · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Radiofrequency ablation (RFA) is the standard of care to cure many cardiac arrhythmias. Epicardial ablation for the treatment of ventricular tachycardia has limited success rates due in part to the presence of epicardial fat, which prevents proper rf energy delivery, inadequate contact of ablation catheter with tissue, and increased likelihood of complications with energy delivery in close proximity to coronary vessels. A method to directly visualize the epicardial surface during RFA could potentially provide feedback to reduce complications and titrate rf energy dose by detecting critical structures, assessing probe contact, and confirming energy delivery by visualizing lesion formation. Currently, there is no technology available for direct visualization of the heart surface during epicardial RFA therapy. We demonstrate that optical coherence tomography (OCT) imaging has the potential to fill this unmet need. Spectral domain OCT at 1310 nm is employed to image the epicardial surface of freshly excised swine hearts using a microscope integrated bench-top scanner and a forward imaging catheter probe. OCT image features are observed that clearly distinguish untreated myocardium, ablation lesions, epicardial fat, and coronary vessels, and assess tissue contact with catheter-based imaging. These results support the potential for real-time guidance of epicardial RFA therapy using OCT imaging.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.