ReviewSeminars in immunopathology2010
Drosophila as a model system to study autophagy.
Review in Seminars in immunopathology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 56 citations in OpenAlex.
- Atg8/LC3 controls systemic nutrient surplus signaling in flies and humans.Current biology : CB · 2024Article
- Review
- Modulation of protease expression by the transcription factor Ptx1/PITX regulates protein quality control during aging.Cell reports · 2023Article
- Article
- Article
- Autophagy inFrontiers in immunology · 2021Review
- The identification of tick autophagy-related genes in Ixodes scapularis responding to amino acid starvation.Ticks and tick-borne diseases · 2020Article
- Recovery from supercooling, freezing, and cryopreservation stress in larvae of the drosophilid fly, Chymomyza costata.Scientific reports · 2018Article
- Basal autophagy is required for promoting dendritic terminal branching in Drosophila sensory neurons.PloS one · 2018Article
- Rapid autophagic regression of the milk gland during involution is critical for maximizing tsetse viviparous reproductive output.PLoS neglected tropical diseases · 2018Article
- Population genetic analysis of autophagy and phagocytosis genes in Drosophila melanogaster and D. simulans.PloS one · 2018Article
- The Fly Way of Antiviral Resistance and Disease Tolerance.Advances in immunology · 2018Review
- Caspase involvement in autophagy.Cell death and differentiation · 2017Review
- Improved annotation of the insect vector of citrus greening disease: biocuration by a diverse genomics community.Database : the journal of biological databases and curation · 2017Article
- Wildtype adult stem cells, unlike tumor cells, are resistant to cellular damages in Drosophila.Developmental biology · 2016Article
- WAC Regulates mTOR Activity by Acting as an Adaptor for the TTT and Pontin/Reptin Complexes.Developmental cell · 2016Article
- FlyBase: establishing a Gene Group resource for Drosophila melanogaster.Nucleic acids research · 2016Article
- Article
- Article
- Melipona quadrifasciata (Hymenoptera: Apidae) fat body persists through metamorphosis with a few apoptotic cells and an increased autophagy.Protoplasma · 2015Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Originally identified as a response to starvation in yeast, autophagy is now understood to fulfill a variety of roles in higher eukaryotes, from the maintenance of cellular homeostasis to the cellular response to stress, starvation, and infection. Although genetics and biochemical studies in yeast have identified many components involved in autophagy, the findings that some of the essential components of the yeast pathway are missing in higher organisms underscore the need to study autophagy in more complex systems. This review focuses on the use of the fruitfly, Drosophila melanogaster as a model system for analysis of autophagy. Drosophila is an organism well-suited for genetic analysis and represents an intermediate between yeast and mammals with respect to conservation of the autophagy machinery. Furthermore, the complex biology and physiology of Drosophila presents an opportunity to model human diseases in a tissue specific and analogous context.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.