ArticleInternational journal of peptides2010
The effect of ingested macronutrients on postprandial ghrelin response: a critical review of existing literature data.
Article in International journal of peptides, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 71 citations in OpenAlex.
- Fat Amount Rather Than Fatty Acid Composition Influences Postprandial Hunger, Satiety and Attention in Men and Women with a Risk Phenotype for Cardiometabolic Diseases: A Randomized Crossover Trial.The Journal of nutrition · 2026Trial
- A high-protein total diet replacement alters the regulation of food intake and energy homeostasis in healthy, normal-weight adults.European journal of nutrition · 2022Trial
- Loneliness predicts postprandial ghrelin and hunger in women.Hormones and behavior · 2015Trial
- Interpersonal stressors predict ghrelin and leptin levels in women.Psychoneuroendocrinology · 2014Trial
- Macronutrient mixtures and interactions in health and disease.Nature reviews. Endocrinology · 2026Review
- Article
- Computationally Modeling the Physiologic Impact of the Ratio of Fats to Carbohydrates in the Diet on Intake Among Metabolically Healthy Adults.Current developments in nutrition · 2025Article
- The Effect of Sleep Disruption on Cardiometabolic Health.Life (Basel, Switzerland) · 2025Review
- Establishing a Female Animal Model of Prediabetes Using a High-Carbohydrate, High-Fat Diet.Current issues in molecular biology · 2024Article
- Non-Classical Aspects of Obesity Pathogenesis and Their Relative Clinical Importance for Obesity Treatment.Healthcare (Basel, Switzerland) · 2023Review
- Influence of food images with different macronutrient compositions on serum ghrelin levels: Analysis in healthy males.Obesity science & practice · 2022Article
- Are the Changes in Gastrointestinal Hormone Secretion Necessary for the Success of Bariatric Surgery? A Critical Review of the Literature.Obesity surgery · 2021Review
- MECHANISMS IN ENDOCRINOLOGY: The gut-brain axis: regulating energy balance independent of food intake.European journal of endocrinology · 2021Review
- Fructose and the Liver.International journal of molecular sciences · 2021Review
- Article
- Gut and Metabolic Hormones Changes After Endoscopic Sleeve Gastroplasty (ESG) Vs. Laparoscopic Sleeve Gastrectomy (LSG).Obesity surgery · 2020Article
- Mental health in the era of COVID-19: prevalence of psychiatric disorders in a cohort of patients with type 1 and type 2 diabetes during the social distancing.Diabetology & metabolic syndrome · 2020Article
- Impact of Pre-Processed Chickpea Flour Incorporation into "Foods (Basel, Switzerland) · 2018Article
- Novel Molecules Regulating Energy Homeostasis: Physiology and Regulation by Macronutrient Intake and Weight Loss.Endocrinology and metabolism (Seoul, Korea) · 2016Review
- The Role of Dietary Protein and Fat in Glycaemic Control in Type 1 Diabetes: Implications for Intensive Diabetes Management.Current diabetes reports · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ghrelin is a powerful orexigenic gut hormone with growth hormone releasing activity. It plays a pivotal role for long-term energy balance and short-term food intake. It is also recognized as a potent signal for meal initiation. Ghrelin levels rise sharply before feeding onset, and are strongly suppressed by food ingestion. Postprandial ghrelin response is totally macronutrient specific in normal weight subjects, but is rather independent of macronutrient composition in obese. In rodents and lean individuals, isoenergetic meals of different macronutrient content suppress ghrelin to a variable extent. Carbohydrate appears to be the most effective macronutrient for ghrelin suppression, because of its rapid absorption and insulin-secreting effect. Protein induces prolonged ghrelin suppression and is considered to be the most satiating macronutrient. Fat, on the other hand, exhibits rather weak and insufficient ghrelin-suppressing capacity. The principal mediators involved in meal-induced ghrelin regulation are glucose, insulin, gastrointestinal hormones released in the postabsorptive phase, vagal activity, gastric emptying rate, and postprandial alterations in intestinal osmolarity.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.