Evidence map›Paper›PMID 20797968›Full record

ArticleThe Journal of general virology2010

Full-length genome sequence of a simian immunodeficiency virus (SIV) infecting a captive agile mangabey (Cercocebus agilis) is closely related to SIVrcm infecting wild red-capped mangabeys (Cercocebus torquatus) in Cameroon.

Steve Ahuka-Mundeke, Florian Liegeois, Ahidjo Ayouba, Yacouba Foupouapouognini, Eric Nerrienet, Eric Delaporte, Martine Peeters

Open access · greenAbstract read
In one paragraph

Article in The Journal of general virology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.4field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Energetic cost of building a virus.Proceedings of the National Academy of Sciences of the United States of America · 2017
    Article
  4. Article
  5. Article
  6. Article
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  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Steve Ahuka-MundekeUMR145, Institut de Recherche pour le Developpement (IRD) and University of Montpellier 1, Montpellier, France.
Florian Liegeois
Ahidjo Ayouba
Yacouba Foupouapouognini
Eric Nerrienet
Eric Delaporte
Martine Peeters
Université de Montpellier · FRCentre Pasteur du Cameroun · CMInstitut de Recherche pour le Développement · FRInstitut Pasteur du Cambodge · KH

Funding

Natural SIV Reservoirs and Human Zoonotic RiskR01AI050529 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI HAHN, BEATRICE H · 2001 to 2022
$6.1M
Natural SIV Reservoirs and Human Zoonotic RiskR37AI050529 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI HAHN, BEATRICE H · 2008 to 2017
$5.7M
NIAID NIH HHS R01 AI050529NIAID NIH HHS R01 AI 50529NIAID NIH HHS R37 AI050529
6 · The paper itself

Abstract

Simian immunodeficiency viruses (SIVs) are lentiviruses that infect an extensive number of wild African primate species. Here we describe for the first time SIV infection in a captive agile mangabey (Cercocebus agilis) from Cameroon. Phylogenetic analysis of the full-length genome sequence of SIVagi-00CM312 showed that this novel virus fell into the SIVrcm lineage and was most closely related to a newly characterized SIVrcm strain (SIVrcm-02CM8081) from a wild-caught red-capped mangabey (Cercocebus torquatus) from Cameroon. In contrast to red-capped mangabeys, no 24 bp deletion in CCR5 has been observed in the agile mangabey. Further studies on wild agile mangabeys are needed to determine whether agile and red-capped mangabeys are naturally infected with the same SIV lineage, or whether this agile mangabey became infected with an SIVrcm strain in captivity. However, our study shows that agile mangabeys are susceptible to SIV infection.

Indexed as

Genome, ViralPhylogenyAnimalsCameroonCercocebusCluster AnalysisMolecular Sequence DataReceptors, CCR5Receptors, VirusRNA, ViralSequence Analysis, DNASequence DeletionSequence HomologySimian Acquired Immunodeficiency SyndromeSimian Immunodeficiency VirusReceptors, CCR5Receptors, VirusRNA, Viral

Identifiers

PMID20797968
PMCPMC3052563
OpenAlexW1978144895

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.