ArticleChronobiology international2010
Working the night shift causes increased vascular stress and delayed recovery in young women.
Article in Chronobiology international, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Shift work and vascular events: systematic review and meta-analysis.BMJ (Clinical research ed.) · 2012Pooled it
- Urinary interleukin-8 is a biomarker of stress in emergency physicians, especially with advancing age--the JOBSTRESS* randomized trial.PloS one · 2013Trial
- Circadian physiology changes with aging: age is just a number, but circadian physiology keeps time.Current opinion in physiology · 2026Article
- Influence of night shift work on circadian heart-rate rhythm in nurses: using a Holter electrocardiogram that can be continuously measured for two weeks.Industrial health · 2024Article
- Influence of Night Shift Work on Heart Rate Variability in an Age- and Gender-Matched Study Group.Journal of cardiovascular development and disease · 2024Article
- Circadian Mechanisms in Brain Fluid Biology.Circulation research · 2024Review
- Pressure Building Against the Clock: The Impact of Circadian Misalignment on Blood Pressure.Current hypertension reports · 2024Review
- Gender and activity disparities in the relationship between circadian syndrome and gallstone disease.Frontiers in endocrinology · 2024Article
- The relationship between sleep quality, snoring symptoms, night shift and risk of stroke in Chinese over 40 years old.Frontiers in aging neuroscience · 2023Article
- A cross-sectional study of the interaction between night shift frequency and age on hypertension prevalence among female nurses.Journal of clinical hypertension (Greenwich, Conn.) · 2022Article
- Shift and night work during pregnancy and preterm birth-a cohort study of Swedish health care employees.International journal of epidemiology · 2022Article
- Molecular link between circadian clocks and cardiac function: a network of core clock, slave clock, and effectors.Current opinion in pharmacology · 2021Review
- Observational
- Circadian rhythms and the molecular clock in cardiovascular biology and disease.Nature reviews. Cardiology · 2019Review
- Serum brain-derived neurotrophic factor predicting reduction in pulse pressure after a one-hour rest in nurses working night shifts.Scientific reports · 2018Article
- Sleep Disturbances as a Risk Factor for Stroke.Journal of stroke · 2018Review
- Increased night duty loading of physicians caused elevated blood pressure and sympathetic tones in a dose-dependent manner.International archives of occupational and environmental health · 2016Observational
- Nonstandard working schedules and health: the systematic search for a comprehensive model.BMC public health · 2015Article
- Self-Reported Recovery from 2-Week 12-Hour Shift Work Schedules: A 14-Day Follow-Up.Safety and health at work · 2015Article
- Neuroendocrine recovery after 2-week 12-h day and night shifts: an 11-day follow-up.International archives of occupational and environmental health · 2015Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Shiftwork has been associated with elevated blood pressure (BP) and decreased heart-rate variability (HRV), factors that may increase the long-term risk of cardiovascular-related mortality and morbidity. This study explored the effect of shiftwork on dynamic changes in autonomic control of HRV (cardiac stress), systolic BP and diastolic BP, i.e., SBP and DBP (vascular stress), and recovery in the same subjects working different shifts. By studying the same subjects, the authors could reduce the effect of possible contribution of between-subject variation from genetic predisposition and environmental factors. The authors recruited 16 young female nurses working rotating shifts--day (08:00-16:00 h), evening (16:00-00:00 h), and night (00:00-08:00 h)--and 6 others working the regular day shift. Each nurse received simultaneous and repeated 48-h ambulatory electrocardiography and BP monitoring during their work day and the following off-duty day. Using a linear mixed-effect model to adjust for day shift, the results of the repeated-measurements and self-comparisons found significant shift differences in vascular stress. While working the night shift, the nurses showed significant increases in vascular stress, with increased SBP of 9.7 mm Hg. The changes of SBP and DBP seemed to peak during waking time at the same time on the day off as they did on the working day. Whereas HRV profiles usually returned to baseline level after each shift, the SBP and DBP of night-shift workers did not completely return to baseline levels the following off-duty day (p < .001). The authors concluded that although the nurses may recover from cardiac stress the first day off following a night shift, they do not completely recover from increases in vascular stress on that day.
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