Evidence map›Paper›PMID 20795743›Full record

ArticleJournal of natural products2010

Eucapsitrione, an anti-Mycobacterium tuberculosis anthraquinone derivative from the cultured freshwater cyanobacterium Eucapsis sp.

Megan Sturdy, Aleksej Krunic, Sanghyun Cho, Scott Franzblau, Jimmy Orjala

Abstract read
In one paragraph

Article in Journal of natural products, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Reduction of Silver Ions by Cell Free Extracts of Westiellopsis sp.International journal of biomaterials · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Megan SturdyDepartment of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, 833 S. Wood Street, Room 539, Chicago, Illinois 60612, USA.
Aleksej Krunic
Sanghyun Cho
Scott Franzblau
Jimmy Orjala

Funding

900MHz NMR for Structural Biology in ChicagoP41GM068944 · NIGMS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI GETTINS, PETER G.W. · 2003 to 2007
$6.2M
Microscale LC-MS and NMR Methodology:Rapid Natural (RMI)R01GM075856 · NIGMS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI ORJALA, JIMMY · 2005 to 2007
$1.1M
NIGMS NIH HHS P41 GM068944NIGMS NIH HHS P41 GM68944NIGMS NIH HHS R01GM0758556NIGMS NIH HHS R01 GM075856
6 · The paper itself

Abstract

Eucapsitrione (1), an anthraquinone derivative with an indeno-anthracene-trione skeleton, was isolated from the cyanobacterium Eucapsis sp. (UTEX 1519) by bioassay-guided fractionation. The chemical structure was determined by analyzing MS and 1D and 2D NMR spectroscopic data. Eucapsitrione (1) showed anti-Mycobacterium tuberculosis activity in the microplate Alamar blue assay and low-oxygen-recovery assay with MIC values of 3.1 and 6.4 microM, respectively.

Indexed as

AnimalsAnthraquinonesAntitubercular AgentsCandida albicansChlorocebus aethiopsCyanobacteriaEscherichia coliFresh WaterMicrobial Sensitivity TestsMolecular StructureMycobacterium smegmatisMycobacterium tuberculosisStaphylococcus aureusVero CellsAnthraquinonesAntitubercular Agentseucapsitrione

Identifiers

PMID20795743
PMCPMC2972581

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.