Evidence map›Paper›PMID 20740650›Full record

ArticleMagnetic resonance in medicine2011

Accelerated cardiac magnetic resonance imaging in the mouse using an eight-channel array at 9.4 Tesla.

Jürgen E Schneider, Titus Lanz, Hannah Barnes, Lee-Anne Stork, Steffen Bohl, Craig A Lygate, Roger J Ordidge, Stefan Neubauer

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Magnetic resonance imaging and spectroscopy of the murine cardiovascular system.American journal of physiology. Heart and circulatory physiology · 2013
    Review
  10. Article
  11. Article
  12. Accelerating cine-MR imaging in mouse hearts using compressed sensing.Journal of magnetic resonance imaging : JMRI · 2011
    Article
  13. First-pass perfusion CMR two days after infarction predicts severity of functional impairment six weeks later in the rat heart.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2011
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jürgen E SchneiderBritish Heart Foundation Experimental MR Unit (BMRU), Department of Cardiovascular Medicine, University of Oxford, Oxford OX3 7BN, United Kingdom. jurgen.schneider@cardiov.ox.ac.uk
Titus Lanz
Hannah Barnes
Lee-Anne Stork
Steffen Bohl
Craig A Lygate
Roger J Ordidge
Stefan Neubauer

Funding

British Heart Foundation BS/06/001British Heart Foundation RE/08/004British Heart Foundation RG/10/002/28187
6 · The paper itself

Abstract

MRI has become an important tool to noninvasively assess global and regional cardiac function, infarct size, or myocardial blood flow in surgically or genetically modified mouse models of human heart disease. Constraints on scan time due to sensitivity to general anesthesia in hemodynamically compromised mice frequently limit the number of parameters available in one imaging session. Parallel imaging techniques to reduce acquisition times require coil arrays, which are technically challenging to design at ultrahigh magnetic field strengths. This work validates the use of an eight-channel volume phased-array coil for cardiac MRI in mice at 9.4 T. Two- and three-dimensional sequences were combined with parallel imaging techniques and used to quantify global cardiac function, T(1)-relaxation times and infarct sizes. Furthermore, the rapid acquisition of functional cine-data allowed for the first time in mice measurement of left-ventricular peak filling and ejection rates under intravenous infusion of dobutamine. The results demonstrate that a threefold accelerated data acquisition is generally feasible without compromising the accuracy of the results. This strategy may eventually pave the way for routine, multiparametric phenotyping of mouse hearts in vivo within one imaging session of tolerable duration.

Indexed as

TransducersAnimalsEquipment DesignEquipment Failure AnalysisImage EnhancementMagnetic Resonance Imaging, CineMagneticsMiceMice, Inbred C57BLReproducibility of ResultsSensitivity and Specificity

Identifiers

PMID20740650
PMCPMC3021721

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.