ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2011
Current quality of life and its determinants among opiate-dependent individuals five years after starting methadone treatment.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
What it found
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Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it, 99 citations in OpenAlex.
- A Meta-Analysis of the Efficacy of Case Management for Substance Use Disorders: A Recovery Perspective.Frontiers in psychiatry · 2019Pooled it
- Impact of extended release naltrexone on health-related quality of life in individuals with legal involvement and opioid use disorders.Substance abuse · 2021Trial
- Efficacy of Cognitive Behavioral Therapy on Opiate Use and Retention in Methadone Maintenance Treatment in China: A Randomised Trial.PloS one · 2015Trial
- Effect of a primary care based brief intervention trial among risky drug users on health-related quality of life.Drug and alcohol dependence · 2014Trial
- Prescription medication exchange patterns among methadone maintenance patients.Drug and alcohol dependence · 2013Trial
- Oral Health-Related Quality of Life and Oral Health Indices in Patients With Opioid Use Disorder Undergoing Methadone Maintenance Treatment.International journal of dentistry · 2025Article
- Exploring perceived quality of life in long-term methadone-dependent patients: a qualitative study.Harm reduction journal · 2024Article
- Loss, liberation, and agency: Patient experiences of methadone treatment at opioid treatment programs during the COVID-19 pandemic.Journal of substance use and addiction treatment · 2024Article
- Characteristics and quality of life of people living with comorbid disorders in substance use recovery residences.Frontiers in public health · 2024Article
- Quality of life and associated factors of heroin-dependent patients receiving methadone and buprenorphine maintenance treatment.Neuropsychopharmacology reports · 2023Article
- The Intersection of Health Rehabilitation Services with Quality of Life in Saudi Arabia: Current Status and Future Needs.Healthcare (Basel, Switzerland) · 2023Review
- Evaluating the Aspects of Quality of Life in Individuals with Substance Use Disorder: A Systematic Review Based on the WHOQOL Questionnaire.Journal of multidisciplinary healthcare · 2023Review
- Quality of life and its correlated factors among patients with substance use disorders: a systematic review and meta-analysis.Archives of public health = Archives belges de sante publique · 2022Article
- Health-related quality of life in outpatients with substance use disorder: evolution over time and associated factors.Health and quality of life outcomes · 2022Article
- Sociodemographic and Clinical Characteristics Associated with Improvements in Quality of Life for Participants with Opioid Use Disorder.Healthcare (Basel, Switzerland) · 2022Article
- Factors associated with quality of life (QOL) scores among methadone patients in Myanmar.PLOS global public health · 2022Article
- Quality of Life and Opioid Use Motives: Direct and Indirect Associations with Risky Opioid Use in a Community Sample of Adults.Substance use & misuse · 2022Article
- Cognitive Impairment in Opium Use Disorder.Behavioural neurology · 2021Article
- Relationship between family functioning and health-related quality of life among methadone maintenance patients: a Bayesian approach.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2020Article
- Psychological distress mediated the effects of self-stigma on quality of life in opioid-dependent individuals: A cross-sectional study.PloS one · 2019Observational
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study explores the current QoL of opiate-dependent individuals who started outpatient methadone treatment at least 5 years ago and assesses the influence of demographic, psychosocial, drug and health-related variables on individuals' QoL.
methodsParticipants (n = 159) were interviewed about their current QoL, psychological distress and severity of drug-related problems, using the Lancashire Quality of Life Profile, the Brief Symptom Inventory and the Addiction Severity Index. Potential determinants of QoL were assessed in a multiple linear regression analysis.
resultsFive years after the start of methadone treatment, opiate-dependent individuals report low QoL scores on various domains. No association was found between drug-related variables and QoL, but a significant negative impact of psychological distress was identified. Severity of psychological distress, taking medication for psychological problems and the inability to change one's living situation were associated with lower QoL. Having at least one good friend and a structured daily activity had a significant, positive impact on QoL.
conclusionsOpiate-dependent individuals' QoL is mainly determined by their psychological well-being and a number of psychosocial variables. These findings highlight the importance of a holistic approach to treatment and support in methadone maintenance treatment, which goes beyond fixing the negative physical consequences of opiate dependence.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.