Evidence map›Paper›PMID 20739627›Full record

ArticleAmerican journal of physiology. Cell physiology2010

Nicotinic receptor signaling in nonexcitable epithelial cells: paradigm shifting from ion current to kinase cascade. Focus on "Upregulation of nuclear factor-kappaB expression by SLURP-1 is mediated by alpha7-nicotinic acetylcholine receptor and involves both ionic events and activation of protein kinases".

Andrzej Slominski

Open access · greenAbstract readCommentEditorial
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Cell physiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Nicotine: From Discovery to Biological Effects.International journal of molecular sciences · 2023
    Review
  2. CHRFAM7A: a human-specific α7-nicotinic acetylcholine receptor gene shows differential responsiveness of human intestinal epithelial cells to LPS.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2015
    Article
  3. Article
  4. Novel cholinergic peptides SLURP-1 and -2 regulate epithelialization of cutaneous and oral wounds.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Andrzej Slominski
University of Tennessee Health Science Center · US

Funding

Novel Biosynthetic Pathway for Secosteroids and the SkinR01AR052190 · NIAMS · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI POSTLETHWAITE, ARNOLD E, SLOMINSKI, ANDRZEJ T · 2006 to 2013
$2.2M
NIAMS NIH HHS AR052190NIAMS NIH HHS R01 AR052190
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

alpha7 Nicotinic Acetylcholine ReceptorAntigens, LyEnzyme ActivationEpithelial CellsHumansNF-kappa BProtein KinasesReceptors, NicotinicSignal TransductionUp-RegulationUrokinase-Type Plasminogen Activatoralpha7 Nicotinic Acetylcholine ReceptorAntigens, LyChrna7 protein, humanNF-kappa BProtein KinasesReceptors, NicotinicSLURP1 protein, humanUrokinase-Type Plasminogen Activator

Identifiers

PMID20739627
PMCPMC2980314
OpenAlexW2142182512

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.