ArticleJournal of clinical microbiology2010
Propionibacterium acnes and Staphylococcus epidermidis isolated from refractory endodontic lesions are opportunistic pathogens.
Article in Journal of clinical microbiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
38 citing papers in PubMed, 97 citations in OpenAlex.
- Evaluation of potential sources of nosocomial infection in endodontic practice: a hygienic study.BDJ open · 2025Article
- Introducing a Novel Paper Point Method for Isolated Apical Sampling-The Controlled Apical Sampling Device: A Methodological Study.Biomedicines · 2025Article
- Apical periodontitis microbiome association with salivary and serum inflammatory burden.International endodontic journal · 2025Article
- Comprehensive lipidomic analysis of the genusmSphere · 2024Article
- Community assembly of the human piercing microbiome.Proceedings. Biological sciences · 2023Article
- Splenic abscess caused byBMJ case reports · 2023Article
- Oral biofilm dysbiosis during experimental periodontitis.Molecular oral microbiology · 2022Article
- Targeting Acne Bacteria and Wound Healing In Vitro UsingPharmaceuticals (Basel, Switzerland) · 2022Article
- High resolution 16S rRNA gene Next Generation Sequencing study of brain areas associated with Alzheimer's and Parkinson's disease.Frontiers in aging neuroscience · 2022Article
- Periodontitis increases risk of viable bacteria in freshly drawn blood donations.Blood transfusion = Trasfusione del sangue · 2021Article
- Sheep as a Potential Model of Intradiscal Infection by the BacteriumVeterinary sciences · 2021Article
- Atrial Natriuretic Peptide Affects Skin CommensalMicroorganisms · 2021Article
- Bacteria Residing at Root Canals Can Induce Cell Proliferation and Alter the Mechanical Properties of Gingival and Cancer Cells.International journal of molecular sciences · 2020Article
- Antimicrobial Effectiveness of Calcium Silicate Sealers against a Nutrient-Stressed Multispecies Biofilm.Journal of clinical medicine · 2020Article
- Microbial Association with GenusAntibiotics (Basel, Switzerland) · 2020Review
- Prevalence of the GenusJournal of clinical medicine · 2020Review
- Prevalence of Bacteria of Genus Actinomyces in Persistent Extraradicular Lesions-Systematic Review.Journal of clinical medicine · 2020Review
- Reduction of an in vitro Intraradicular Multispecies Biofilm Using Two Rotary Instrumentation Sequences.European journal of dentistry · 2020Article
- Cardiac Tamponade Caused byThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2020Review
- Review
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The predominant cultivable microbiota from 20 refractory endodontic lesions (9 with abscesses and 11 without abscesses) were determined, and Propionibacterium acnes and Staphylococcus epidermidis were among the most predominant organisms. The number of species identified from lesions with abscesses (14.1 ± 2.6) was significantly greater (P < 0.001) than the number from lesions without abscesses (7.4 ± 5.9). Comparison of perioral isolates using repetitive extragenic palindromic PCR of the same species from the same subjects demonstrated that the endodontic and skin populations were significantly different. The P. acnes isolates were typed on the basis of recA gene sequence comparison, and only three types (types I, II, and III) were identified among 125 isolates examined. However, we found that type I (type IA and IB) isolates were primarily isolated from the skin, while types II and III were significantly more likely to be isolated from the endodontic lesions (P < 10(-10)). We found that the robustness of the recA phylotypes was not strong by comparing the partial gene sequences of six putative virulence determinants, PAmce, PAp60, PA-25957, PA-5541, PA-21293, and PA-4687. The resulting neighbor-joining trees were incongruent, and significant (phi test; P = 2.2 × 10(-7)) evidence of recombination was demonstrated, with significant phylogenetic heterogeneity being apparent within the clusters. P. acnes and S. epidermidis isolated from refractory endodontic infections, with or without periapical abscesses, are likely to be nosocomial infections.
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Registered trials
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