Evidence map›Paper›PMID 20739176›Full record

ReviewCurrent opinion in structural biology2010

From structure to cellular mechanism with infrared microspectroscopy.

Lisa M Miller, Paul Dumas

Abstract readReview
In one paragraph

Review in Current opinion in structural biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

  1. Article
  2. Effects ofAnimals : an open access journal from MDPI · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Electromagnetic characteristics ofFrontiers in bioengineering and biotechnology · 2022
    Article
  12. Article
  13. Review
  14. Article
  15. Super-Resolution Infrared Imaging of Polymorphic Amyloid Aggregates Directly in Neurons.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2020
    Article
  16. Assessing two-way interactions between cells and inorganic nanoparticles.Journal of materials science. Materials in medicine · 2019
    Article
  17. Biochemical similarity between cultured chondrocytes andBiotechnology reports (Amsterdam, Netherlands) · 2019
    Article
  18. Assessment of By-Product fromMolecules (Basel, Switzerland) · 2019
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Lisa M MillerNational Synchrotron Light Source, Brookhaven National Laboratory, Upton, NY, USA. lmiller@bnl.gov
Paul Dumas

Funding

Metals and Protein Structure in Protein-Folding DiseasesR01GM066873 · NIGMS · BROOKHAVEN SCIENCE ASSOC-BROOKHAVEN LAB · PI MILLER, LISA M · 2003 to 2007
$984k
NIGMS NIH HHS R01 GM066873
6 · The paper itself

Abstract

Current efforts in structural biology aim to integrate structural information within the context of cellular organization and function. X-rays and infrared radiation stand at opposite ends of the electromagnetic spectrum and act as complementary probes for achieving this goal. Intense and bright beams are produced by synchrotron radiation, and are efficiently used in the wavelength domain extending from hard X-rays to the far-infrared (or THz) regime. While X-ray crystallography provides exquisite details on atomic structure, Fourier transform infrared microspectroscopy (FTIRM) is emerging as a spectroscopic probe and imaging tool for correlating molecular structure to biochemical dynamics and function. In this manuscript, the role of synchrotron FTIRM in bridging the gap towards 'functional biology' is discussed based upon recent achievements, with a critical assessment of the contributions to biological and biomedical research.

Indexed as

AnimalsCellsCells, CulturedHumansMicrospectrophotometryMolecular ImagingSpectrophotometry, InfraredSpectroscopy, Fourier Transform Infrared

Identifiers

PMID20739176
PMCPMC4140183

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.