ArticleBMC infectious diseases2010
Seroepidemiology of pandemic influenza A (H1N1) 2009 virus infections in Pune, India.
Article in BMC infectious diseases, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 3 of them syntheses that pooled it.
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Who cites it
41 citing papers in PubMed, 3 syntheses or guidelines pooled it, 67 citations in OpenAlex.
- Pooled it
- Review Article: The Fraction of Influenza Virus Infections That Are Asymptomatic: A Systematic Review and Meta-analysis.Epidemiology (Cambridge, Mass.) · 2015Pooled it
- Estimating age-specific cumulative incidence for the 2009 influenza pandemic: a meta-analysis of A(H1N1)pdm09 serological studies from 19 countries.Influenza and other respiratory viruses · 2013Pooled it
- Trial
- Will COVID-19 become mild, like a cold?Epidemiology and infection · 2024Review
- Article
- A Modern Perspective on Vaccinating Healthcare Service Providers in India: A Narrative Review.Infectious diseases and therapy · 2022Review
- Temperature dependent viral tropism: understanding viral seasonality and pathogenicity as applied to the avoidance and treatment of endemic viral respiratory illnesses.Reviews in medical virology · 2022Review
- Seroprevalence of influenza A H1N1 (swine) infection in the human population in a cantonment.Medical journal, Armed Forces India · 2019Article
- Public Health Policy and Experience of the 2009 H1N1 Influenza Pandemic in Pune, India.International journal of health policy and management · 2018Review
- Influenza A(H1N1)pdm09 outbreak detected in inter-seasonal months during the surveillance of influenza-like illness in Pune, India, 2012-2015.Epidemiology and infection · 2017Article
- Seroepidemiology of parvovirus B19 among different age groups & pregnant women in India.The Indian journal of medical research · 2017Article
- When treating rheumatoid arthritis be vigilant for influenza (& pneumonia): Don't ignore, don't neglect.The Indian journal of medical research · 2017Article
- Effect of disease-modifying antirheumatic drug therapy on immune response to trivalent influenza vaccine in rheumatoid arthritis.The Indian journal of medical research · 2017Article
- Seasonality and selective trends in viral acute respiratory tract infections.Medical hypotheses · 2016Article
- Article
- Incidence of symptomatic A(H1N1)pdm09 influenza during the pandemic and post-pandemic periods in a rural Indian community.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2013Article
- Knowledge, attitude, and practices about the seasonal influenza vaccination among healthcare workers in Srinagar, India.Influenza and other respiratory viruses · 2013Article
- Influenza serological studies to inform public health action: best practices to optimise timing, quality and reporting.Influenza and other respiratory viruses · 2013Article
- Seroprevalence of pandemic influenza H1N1 (2009) & seasonal influenza viruses in pigs in Maharashtra & Gujarat States, India, 2011.The Indian journal of medical research · 2013Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn India, Pune was one of the badly affected cities during the influenza A (H1N1) 2009 pandemic. We undertook serosurveys among the risk groups and general population to determine the extent of pandemic influenza A (H1N1) 2009 virus infections.
methodsPre-pandemic sera from the archives, collected during January 2005 to March 2009, were assayed for the determination of baseline seropositivity. Serosurveys were undertaken among the risk groups such as hospital staff, general practitioners, school children and staff and general population between 15th August and 11th December 2009. In addition, the PCR-confirmed pandemic influenza A (H1N1) 2009 cases and their household contacts were also investigated. Haemagglutination-inhibition (HI) assays were performed using turkey red blood cells employing standard protocols. A titre of >or=1:40 was considered seropositive.
resultsOnly 2 (0.9%) of the 222 pre-pandemic sera were positive. The test-retest reliability of HI assay in 101 sera was 98% for pandemic H1N1, 93.1% for seasonal H1N1 and 94% for seasonal H3N2. The sera from 48 (73.8%) of 65 PCR-confirmed pandemic H1N1 cases in 2009 were positive. Seropositivity among general practitioners increased from 4.9% in August to 9.4% in November and 15.1% in December. Among hospital staff, seropositivity increased from 2.8% in August to 12% in November. Seropositivity among the schools increased from 2% in August to 10.7% in September. The seropositivity among students (25%) was higher than the school staff in September. In a general population survey in October 2009, seropositivity was higher in children (9.1%) than adults (4.3%). The 15-19 years age group showed the highest seropositivity of 20.3%. Seropositivity of seasonal H3N2 (55.3%) and H1N1 (26.4%) was higher than pandemic H1N1 (5.7%) (n = 2328). In households of 74 PCR-confirmed pandemic H1N1 cases, 25.6% contacts were seropositive. Almost 90% pandemic H1N1 infections were asymptomatic or mild. Considering a titre cut off of 1:10, seropositivity was 1.5-3 times as compared to 1:40.
conclusionsPandemic influenza A (H1N1) 2009 virus infection was widespread in all sections of community. However, infection was significantly higher in school children and general practitioners. Hospital staff had the lowest infections suggesting the efficacy of infection-control measures.
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