Evidence map›Paper›PMID 20738104›Full record

ArticleOrganic letters2010

Aziridinomitosanes via lactam cyclization.

Susan D Wiedner, Edwin Vedejs

Abstract read
In one paragraph

Article in Organic letters, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Crystal structure ofActa crystallographica. Section E, Crystallographic communications · 2021
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Susan D WiednerDepartment of Chemistry, University of Michigan, 930 North University Avenue, Ann Arbor, Michigan 48109, USA.
Edwin Vedejs

Funding

CYTOTOXIC NITROGEN HETEROCYCLESR01CA017918 · NCI · UNIVERSITY OF WISCONSIN MADISON · PI VEDEJS, EDWIN · 1985 to 2008
$2.7M
NCI NIH HHS CA17918NCI NIH HHS R01 CA017918
6 · The paper itself

Abstract

Aziridinomitosane ketones 4 and 24 are accessed by internal acyl anion equivalent-lactam cyclization of 29 in a convergent route. The key aziridinolactam 6 is prepared by tin-lithium exchange via the lithiated aziridine 11.

Indexed as

AziridinesCatalysisCyclizationMitomycinsMolecular StructureStereoisomerismaziridineAziridinesMitomycinsmitosane

Identifiers

PMID20738104
PMCPMC2946824

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.