Evidence map›Paper›PMID 20737446›Full record

ArticleElectrophoresis2010

Parallel separations using capillary electrophoresis on a multilane microchip with multiplexed laser-induced fluorescence detection.

Irena Nikcevic, Aigars Piruska, Kenneth R Wehmeyer, Carl J Seliskar, Patrick A Limbach, William R Heineman

Abstract read
In one paragraph

Article in Electrophoresis, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Irena NikcevicDepartment of Chemistry, University of Cincinnati, Cincinnati, OH, USA.
Aigars Piruska
Kenneth R Wehmeyer
Carl J Seliskar
Patrick A Limbach
William R Heineman

Funding

Bioassays and Molecular Characterization by Microchip CER01GM069547 · NIGMS · UNIVERSITY OF CINCINNATI · PI LIMBACH, PATRICK A · 2004 to 2007
$1.4M
NIGMS NIH HHS GM 69547NIGMS NIH HHS R01 GM069547
6 · The paper itself

Abstract

Parallel separations using CE on a multilane microchip with multiplexed LIF detection is demonstrated. The detection system was developed to simultaneously record data on all channels using an expanded laser beam for excitation, a camera lens to capture emission, and a CCD camera for detection. The detection system enables monitoring of each channel continuously and distinguishing individual lanes without significant crosstalk between adjacent lanes. Multiple analytes can be determined in parallel lanes within a single microchip in a single run, leading to increased sample throughput. The pK(a) determination of small molecule analytes is demonstrated with the multilane microchip.

Indexed as

Microchip Analytical ProceduresMicrofluidicsBenzopyransCarboxylic AcidsElectrophoresis, CapillaryFluoresceinFluorescent DyesHydrogen-Ion ConcentrationKineticsLasersNaphtholsRhodaminesSpectrometry, FluorescenceBenzopyransCarboxylic AcidsFluoresceinFluorescent DyesNaphtholsOregon Green 488 carboxylic acidRhodaminesseminaphthorhodaminefluoride

Identifiers

PMID20737446
PMCPMC3031587

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.