Evidence map›Paper›PMID 20737275›Full record

ArticleEuropean archives of psychiatry and clinical neuroscience2011

Transcranial magnetic stimulation for the treatment of depression: feasibility and results under naturalistic conditions: a retrospective analysis.

Elmar Frank, Peter Eichhammer, Julia Burger, Marc Zowe, Michael Landgrebe, Göran Hajak, Berthold Langguth

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Article in European archives of psychiatry and clinical neuroscience, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Trial
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  5. Article
  6. Observational
  7. Developments in treating the nonmotor symptoms of stroke.Expert review of neurotherapeutics · 2020
    Review
  8. Cortical stimulation in conscious rats controls joint inflammation.Progress in neuro-psychopharmacology & biological psychiatry · 2018
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Pain, affect and psychotic illness.European archives of psychiatry and clinical neuroscience · 2011
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Elmar FrankDepartment of Psychiatry, Psychosomatic Medicine and Psychotherapy, University of Regensburg, Universitätsstraße 84, Regensburg, Germany.
Peter Eichhammer
Julia Burger
Marc Zowe
Michael Landgrebe
Göran Hajak
Berthold Langguth

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An increasing number of controlled studies strongly support an antidepressant effect of high-frequency repetitive transcranial magnetic stimulation (rTMS) over the left dorsolateral prefrontal cortex. However, these data come from highly selected study populations. Whether rTMS is a feasible therapeutic tool for the treatment of depression under naturalistic condition has not yet been addressed. Here, we report results from 232 depressive patients [aged 20-76 years, baseline Hamilton Depression Rating Score (HDRS-21) 24.0 ± 7.3] treated with rTMS add-on to continued psychopharmacological treatment in a naturalistic clinical setting. Two thousand stimuli of 20-Hz rTMS were applied daily over the left dorsolateral prefrontal cortex with an intensity of 110% of motor threshold. Treatment duration was individually planned and varied between 10 and 20 sessions. In average, patients received 13 ± 6.1 rTMS sessions. In 90% of the cases, treatment was terminated regularly. No severe side effects were observed. Only four patients stopped rTMS treatment because of side effects. Ratings with the HDRS-21 before and after treatment were available in 130 patients. The average improvement of the HDRS-21 in this subsample was 9.0 ± 9.2 points. Fifty-three patients had an improvement of 50% or more. These results document that rTMS is feasible, safe and well tolerated under naturalistic conditions.

Indexed as

AdultAgedDepressionFeasibility StudiesFemaleFunctional LateralityHumansMaleMiddle AgedPrefrontal CortexPsychiatric Status Rating ScalesRetrospective StudiesTranscranial Magnetic StimulationTreatment OutcomeYoung Adult

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.