Evidence map›Paper›PMID 20737144›Full record

ArticlePediatric radiology2010

Can induced hypothermia be assured during brain MRI in neonates with hypoxic-ischemic encephalopathy?

Pia Wintermark, Michelle Labrecque, Simon K Warfield, Stephanie DeHart, Anne Hansen

Abstract read
In one paragraph

Article in Pediatric radiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 34 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Neuroimaging in the term newborn with neonatal encephalopathy.Seminars in fetal & neonatal medicine · 2021
    Review
  6. Article
  7. Article
  8. Article
  9. Article
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  11. Article
  12. Review
  13. Observational
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Pia WintermarkDivision of Newborn Medicine, Children's Hospital Boston, Boston, MA, USA. Pia.Wintermark@bluemail.ch
Michelle Labrecque
Simon K Warfield
Stephanie DeHart
Anne Hansen
Boston Children's Hospital · US

Funding

SYNAPTIC MECHANISMS IN HIPPOCAMPAL EPILEPTOGENESISP30HD018655 · NICHD · CHILDREN'S HOSPITAL BOSTON · PI POMEROY, SCOTT LOREN · 1985 to 2015
$26.2M
Bioinformatics Software for MRI of Brain DevelopmentR01RR021885 · NCRR · BOSTON CHILDREN'S HOSPITAL · PI WARFIELD, SIMON K · 2006 to 2009
$1.6M
Bioinformatics Tools for Multi-Center Diagnostic TrialsR01GM074068 · NIGMS · BRIGHAM AND WOMEN'S HOSPITAL · PI WARFIELD, SIMON K · 2006 to 2008
$666k
Improved Interoperability and Dissemination of Software for Simultaneous Truth anR03EB008680 · NIBIB · BOSTON CHILDREN'S HOSPITAL · PI WARFIELD, SIMON K · 2009 to 2009
$171k
NCRR NIH HHS R01 RR021885NIBIB NIH HHS R03 EB008680NICHD NIH HHS P30 HD018655NIGMS NIH HHS R01 GM074068
6 · The paper itself

Abstract

Until now, brain MRIs in asphyxiated neonates who are receiving therapeutic hypothermia have been performed after treatment is complete. However, there is increasing interest in utilizing early brain MRI while hypothermia is still being provided to rapidly understand the degree of brain injury and possibly refine neuroprotective strategies. This study was designed to assess whether therapeutic hypothermia can be maintained while performing a brain MRI. Twenty MRI scans were obtained in 12 asphyxiated neonates while they were treated with hypothermia. The median difference between esophageal temperature on NICU departure and return was 0.1°C (range: -0.8 to 0.8°C). We found that therapeutic hypothermia can be safely and reproducibly maintained during a brain MRI. Hypothermia treatment should not prevent obtaining an early brain MRI if clinically indicated.

Indexed as

BrainFemaleHumansHypothermia, InducedHypoxia-Ischemia, BrainInfant, NewbornMagnetic Resonance ImagingMalePrognosisReproducibility of ResultsSensitivity and SpecificityTreatment Outcome

Identifiers

PMID20737144
PMCPMC3335293
OpenAlexW2020281304

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.