ArticleEuropean journal of human genetics : EJHG2011
A genomic analysis identifies a novel component in the genetic structure of sub-Saharan African populations.
Article in European journal of human genetics : EJHG, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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21 citing papers in PubMed, 39 citations in OpenAlex.
- Responding to the call: Population affinity estimation in a South African forensic context of identification - are we helping or harming?Forensic science international. Synergy · 2025Article
- Genetic structure correlates with ethnolinguistic diversity in eastern and southern Africa.American journal of human genetics · 2022Article
- Assessing the importance of cultural diffusion in the Bantu spread into southeastern Africa.PloS one · 2019Article
- Genome-Wide SNP Analysis of Southern African Populations Provides New Insights into the Dispersal of Bantu-Speaking Groups.Genome biology and evolution · 2015Article
- The genetics of East African populations: a Nilo-Saharan component in the African genetic landscape.Scientific reports · 2015Article
- Genetic variation reveals large-scale population expansion and migration during the expansion of Bantu-speaking peoples.Proceedings. Biological sciences · 2014Article
- Genetic variation and adaptation in Africa: implications for human evolution and disease.Cold Spring Harbor perspectives in biology · 2014Review
- Inducible nitric oxide synthase drives mTOR pathway activation and proliferation of human melanoma by reversible nitrosylation of TSC2.Cancer research · 2014Article
- Migration and interaction in a contact zone: mtDNA variation among Bantu-speakers in Southern Africa.PloS one · 2014Article
- Prevalence of glaucoma in an urban West African population: the Tema Eye Survey.JAMA ophthalmology · 2013Article
- Mitochondrial DNA diversity in two ethnic groups in southeastern Kenya: perspectives from the northeastern periphery of the Bantu expansion.American journal of physical anthropology · 2013Article
- Prediction of people's origin from degraded DNA--presentation of SNP assays and calculation of probability.International journal of legal medicine · 2013Article
- The influence of habitats on female mobility in Central and Western Africa inferred from human mitochondrial variation.BMC evolutionary biology · 2013Article
- Blindness and visual impairment in an urban West African population: the Tema Eye Survey.Ophthalmology · 2012Article
- Bringing together linguistic and genetic evidence to test the Bantu expansion.Proceedings. Biological sciences · 2012Article
- A quantitative comparison of the similarity between genes and geography in worldwide human populations.PLoS genetics · 2012Article
- An early divergence of KhoeSan ancestors from those of other modern humans is supported by an ABC-based analysis of autosomal resequencing data.Molecular biology and evolution · 2012Article
- Development of a panel of genome-wide ancestry informative markers to study admixture throughout the Americas.PLoS genetics · 2012Article
- Hunter-gatherer genomic diversity suggests a southern African origin for modern humans.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- Y-chromosomal variation in sub-Saharan Africa: insights into the history of Niger-Congo groups.Molecular biology and evolution · 2011Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Studies of large sets of single nucleotide polymorphism (SNP) data have proven to be a powerful tool in the analysis of the genetic structure of human populations. In this work, we analyze genotyping data for 2841 SNPs in 12 sub-Saharan African populations, including a previously unsampled region of southeastern Africa (Mozambique). We show that robust results in a world-wide perspective can be obtained when analyzing only 1000 SNPs. Our main results both confirm the results of previous studies, and show new and interesting features in sub-Saharan African genetic complexity. There is a strong differentiation of Nilo-Saharans, much beyond what would be expected by geography. Hunter-gatherer populations (Khoisan and Pygmies) show a clear distinctiveness with very intrinsic Pygmy (and not only Khoisan) genetic features. Populations of the West Africa present an unexpected similarity among them, possibly the result of a population expansion. Finally, we find a strong differentiation of the southeastern Bantu population from Mozambique, which suggests an assimilation of a pre-Bantu substrate by Bantu speakers in the region.
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