Evidence map›Paper›PMID 20735924›Full record

ArticleEmerging infectious diseases2010

Determinants of multidrug-resistant tuberculosis clusters, California, USA, 2004-2007.

John Z Metcalfe, Elizabeth Y Kim, S-Y Grace Lin, Adithya Cattamanchi, Peter Oh, Jennifer Flood, Philip C Hopewell, Midori Kato-Maeda

Open access · diamondAbstract read
In one paragraph

Article in Emerging infectious diseases, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Molecular epidemiology of tuberculosis in foreign-born persons living in San Francisco.American journal of respiratory and critical care medicine · 2013
    Article
  7. Factors associated with genotype clustering of Mycobacterium tuberculosis isolates in an ethnically diverse region of southern California, United States.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2012
    Article
  8. Mycobacterium tuberculosis lineage--what's in your lungs?Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2012
    Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

John Z MetcalfeUniversity of California, San Francisco, California, USA. john.metcalfe@ucsf.edu
Elizabeth Y Kim
S-Y Grace Lin
Adithya Cattamanchi
Peter Oh
Jennifer Flood
Philip C Hopewell
Midori Kato-Maeda
University of California, San Francisco · USCalifornia Department of Public Health · US

Funding

MUTIDISCIPLINARY TRAINING PROGRAM IN LUNG DISEASEST32HL007185 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI David J Erle, LAURENCE HUANG · 1985 to 2026
$24.6M
POPULATION-BASED MOLECULAR EPIDEMIOLOGY OF TUBERCULOSISR01AI034238 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HOPEWELL, PHILIP C · 1993 to 2010
$9.3M
Immunodiagnosis of Active Tuberculosis in HIV-infected PatientsK23HL094141 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CATTAMANCHI, ADITHYA · 2009 to 2013
$760k
NHLBI NIH HHS K23 HL094141NHLBI NIH HHS T32 HL007185NIAID NIH HHS R01 AI034238
6 · The paper itself

Abstract

Laboratory and epidemiologic evidence suggests that pathogen-specific factors may affect multidrug-resistant (MDR) tuberculosis (TB) transmission and pathogenesis. To identify demographic and clinical characteristics of MDR TB case clustering and to estimate the effect of specific isoniazid resistance-conferring mutations and strain lineage on genotypic clustering, we conducted a population-based cohort study of all MDR TB cases reported in California from January 1, 2004, through December 31, 2007. Of 8,899 incident culture-positive cases for which drug susceptibility information was available, 141 (2%) were MDR. Of 123 (87%) strains with genotype data, 25 (20%) were aggregated in 8 clusters; 113 (92%) of all MDR TB cases and 21 (84%) of clustered MDR TB cases occurred among foreign-born patients. In multivariate analysis, the katG S315T mutation (odds ratio 11.2, 95% confidence interval 2.2-Yen; p = 0.004), but not strain lineage, was independently associated with case clustering.

Indexed as

AdolescentAdultAntitubercular AgentsBacterial ProteinsCaliforniaCatalaseCluster AnalysisDrug Resistance, Multiple, BacterialFemaleGenes, BacterialGenotypeHumansIsoniazidMaleMiddle AgedMolecular EpidemiologyAntitubercular AgentsBacterial ProteinsCatalaseIsoniazidkatG protein, Mycobacterium tuberculosisRifampin

Identifiers

PMID20735924
PMCPMC3294976
OpenAlexW2125533755

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.