Trial reportBMC infectious diseases2010
Effectiveness of alcohol-based hand disinfectants in a public administration: impact on health and work performance related to acute respiratory symptoms and diarrhoea.
Trial report in BMC infectious diseases, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03454009 (Kent State University / Price Chopper Wellness Promotion Study), which is not on this map. Cited by 29 papers, 11 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Kent State University / Price Chopper Wellness Promotion Study
Who cites it
29 citing papers in PubMed, 11 syntheses or guidelines pooled it.
- Physical interventions to interrupt or reduce the spread of respiratory viruses.The Cochrane database of systematic reviews · 2023Pooled it
- Interventions to increase personal protective behaviours to limit the spread of respiratory viruses: A rapid evidence review and meta-analysis.British journal of health psychology · 2022Pooled it
- Pooled it
- A Systematic Review for Effective Preventive Public Education of Respiratory Infection.International journal of environmental research and public health · 2021Pooled it
- Hand-washing promotion for preventing diarrhoea.The Cochrane database of systematic reviews · 2021Pooled it
- Physical interventions to interrupt or reduce the spread of respiratory viruses.The Cochrane database of systematic reviews · 2020Pooled it
- ACG Clinical Guideline: Diagnosis, Treatment, and Prevention of Acute Diarrheal Infections in Adults.The American journal of gastroenterology · 2016Guideline
- Hand washing promotion for preventing diarrhoea.The Cochrane database of systematic reviews · 2015Pooled it
- Hand hygiene and risk of influenza virus infections in the community: a systematic review and meta-analysis.Epidemiology and infection · 2014Pooled it
- Hand hygiene to reduce community transmission of influenza and acute respiratory tract infection: a systematic review.Influenza and other respiratory viruses · 2013Pooled it
- Physical interventions to interrupt or reduce the spread of respiratory viruses.The Cochrane database of systematic reviews · 2011Pooled it
- Impact of a Comprehensive Workplace Hand Hygiene Program on Employer Health Care Insurance Claims and Costs, Absenteeism, and Employee Perceptions and Practices.Journal of occupational and environmental medicine · 2016Trial
- Outcomes of a pilot hand hygiene randomized cluster trial to reduce communicable infections among US office-based employees.Journal of occupational and environmental medicine · 2015Trial
- Sustained improvements in handwashing indicators more than 5 years after a cluster-randomised, community-based trial of handwashing promotion in Karachi, Pakistan.Tropical medicine & international health : TM & IH · 2013Trial
- Trial
- Article
- S2k-Guideline hand antisepsis and hand hygiene.GMS hygiene and infection control · 2024Article
- Nonpharmaceutical interventions to prevent viral respiratory infection in community settings: an umbrella review.ERJ open research · 2022Review
- Hand sanitizers as a preventive measure in COVID-19 pandemic, its characteristics, and harmful effects: a review.The Journal of the Egyptian Public Health Association · 2022Review
- Canadian policy changes for alcohol-based hand rubs during the COVID-19 pandemic and unintended risks.World medical & health policy · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe economical impact of absenteeism and reduced productivity due to acute infectious respiratory and gastrointestinal disease is normally not in the focus of surveillance systems and may therefore be underestimated. However, large community studies in Europe and USA have shown that communicable diseases have a great impact on morbidity and lead to millions of lost days at work, school and university each year. Hand disinfection is acknowledged as key element for infection control, but its effect in open, work place settings is unclear.
methodsOur study involved a prospective, controlled, intervention-control group design to assess the epidemiological and economical impact of alcohol-based hand disinfectants use at work place. Volunteers in public administrations in the municipality of the city of Greifswald were randomized in two groups. Participants in the intervention group were provided with alcoholic hand disinfection, the control group was unchanged. Respiratory and gastrointestinal symptoms and days of work were recorded based on a monthly questionnaire over one year. On the whole, 1230 person months were evaluated.
resultsHand disinfection reduced the number of episodes of illness for the majority of the registered symptoms. This effect became statistically significant for common cold (OR = 0.35 [0.17 - 0.71], p = 0.003), fever (OR = 0.38 [0.14-0.99], p = 0.035) and coughing (OR = 0.45 [0.22 - 0.91], p = 0.02). Participants in the intervention group reported less days ill for most symptoms assessed, e.g. colds (2.07 vs. 2.78%, p = 0.008), fever (0.25 vs. 0.31%, p = 0.037) and cough (1.85 vs. 2.00%, p = 0.024). For diarrhoea, the odds ratio for being absent became statistically significant too (0.11 (CI 0.01 - 0.93).
conclusionHand disinfection can easily be introduced and maintained outside clinical settings as part of the daily hand hygiene. Therefore it appears as an interesting, cost-efficient method within the scope of company health support programmes. TRIAL REGISTRATION NUMBER: ISRCTN96340690.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.