SynthesisPediatric surgery international2011
A meta-analysis of outcomes after open and laparoscopic Nissen's fundoplication for gastro-oesophageal reflux disease in children.
Synthesis in Pediatric surgery international, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- A systematic review of the quality of conduct and reporting of systematic reviews and meta-analyses in paediatric surgery.PloS one · 2017Pooled it
- EAES recommendations for the management of gastroesophageal reflux disease.Surgical endoscopy · 2014Guideline
- Partial versus complete fundoplication for the correction of pediatric GERD: a systematic review and meta-analysis.PloS one · 2014Pooled it
- Complete versus partial fundoplication in children with gastroesophageal reflux disease: results of a systematic review and meta-analysis.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2013Pooled it
- Predictors of multiple readmissions or death in the first year after Nissen fundoplication in children.Pediatric surgery international · 2019Article
- Safety of laparoscopic fundoplication in children under 5 kg: a comparative study.Surgical endoscopy · 2018Observational
- Laparoscopic Nissen fundoplication for gastro-oesophageal reflux disease in infants.Pediatric surgery international · 2015Article
- Outcomes of pediatric laparoscopic fundoplication: a critical review of the literature.Canadian journal of gastroenterology & hepatology · 2014Review
- Grand challenge: on the way to scarless visceral surgery.Frontiers in surgery · 2014Article
- Extending Barrett's esophagus cancer risk profile towards genetic abnormalities.Molecular cytogenetics · 2013Article
- Radial esophageal acid exposure and the dilated distal esophagus.Journal of gastroenterology · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The objective of this study is to meta-analyse the published literature comparing outcomes after open (ONF) versus laparoscopic Nissen fundoplication (LNF) for gastro-oesophageal reflux disease in children. Electronic databases were searched from January 1993 to October 2009. A systematic review was performed to obtain a summative outcome. Six comparative studies were analysed. There were 466 patients in the laparoscopic group and 255 in the open group. There was no significant difference in operative time between LNF compared with ONF (p = 0.35). Children stayed in hospital for less time after undergoing LNF compared with ONF [random effects model: SMD = 0.93, 95% CI (0.41, 1.44), z = 3.53, p < 0.01]. Children feed earlier after LNF [random effects model: SMD = 4.13, 95% CI (1.00, 7.27), z = 2.58, p < 0.001] and had less morbidity [fixed effects model: RR = 3.22, 95% CI (1.98, 5.25), z = 4.71, p < 0.01; random effects model: RR = 2.90, 95% CI (1.49, 5.66), z = 3.12, p < 0.01]. No difference in recurrence at 12 months was highlighted (p = 0.29). In conclusion, the laparoscopic Nissen's fundoplication in children may be considered a safe and effective alternative to open surgery; however, careful case selection is required.
Indexed as
Identifiers
20734053What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.