Evidence map›Paper›PMID 20733546›Full record

ArticleMolecules (Basel, Switzerland)2010

Click reactions and boronic acids: applications, issues, and potential solutions.

Chaofeng Dai, Yunfeng Cheng, Jianmei Cui, Binghe Wang

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 41 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Chaofeng DaiDepartment of Chemistry and Center for Biotechnology and Drug Design, Georgia State University, Atlanta, Georgia 30303, USA.
Yunfeng Cheng
Jianmei Cui
Binghe Wang
Georgia State University · US

Funding

Selection of Boronic Acid-modified Aptamers for GlycoproteinsR01GM084933 · NIGMS · GEORGIA STATE UNIVERSITY · PI WANG, BINGHE · 2008 to 2011
$1.2M
Aptamer-based Glycomics ToolsR42GM086925 · NIGMS · ECHELON BIOSCIENCES, INC. · PI WANG, BINGHE · 2009 to 2010
$555k
NIGMS NIH HHS GM084933NIGMS NIH HHS GM086925NIGMS NIH HHS R01 GM084933NIGMS NIH HHS R42 GM086925
6 · The paper itself

Abstract

Boronic acids have been widely used in a wide range of organic reactions, in the preparation of sensors for carbohydrates, and as potential pharmaceutical agents. With the growing importance of click reactions, inevitably they are also applied to the synthesis of compounds containing the boronic acid moiety. However, such applications have unique problems. Chief among them is the issue of copper-mediated boronic acid degradation in copper-assisted [2,3]-cycloadditions involving an alkyne and an azido compound as the starting materials. This review summarizes recent developments, analyzes potential issues, and discusses known as well as possible solutions.

Indexed as

AlkynesBoronic AcidsChemistry, InorganicCopperDNAThymine NucleotidesAlkynesBoronic AcidsCopperDNAthymidine 5'-triphosphateThymine Nucleotides

Identifiers

PMID20733546
PMCPMC6257766
OpenAlexW2014968289

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.