Evidence map›Paper›PMID 20732435›Full record

ReviewBiology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation2011

Strategies to prevent EBV reactivation and posttransplant lymphoproliferative disorders (PTLD) after allogeneic stem cell transplantation in high-risk patients.

Nishitha Reddy, Katayoun Rezvani, A John Barrett, Bipin N Savani

Open access · bronzeAbstract readReview
In one paragraph

Review in Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 85 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Nishitha ReddyHematology and Stem Cell Transplantation Section, Division of Hematology/Oncology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37232-5505, USA.
Katayoun Rezvani
A John Barrett
Bipin N Savani
Vanderbilt University Medical Center · USHammersmith Hospital · GBNational Heart Lung and Blood Institute · US

Funding

improving outcomes after stem cell transplantationZIAHL006105 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI BARRETT, AUSTIN JOHN · 2011 to 2017
$11.5M
Immunobiology and immunotherapy of leukemiaZIAHL006106 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI BARRETT, AUSTIN JOHN · 2011 to 2017
$8.6M
Characterization and improvement of graft versus leukemia effectsZIAHL006107 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI BARRETT, AUSTIN JOHN · 2011 to 2017
$8.6M
Graft-versus-leukemiaZIAHL002342 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI BARRETT, AUSTIN JOHN · 2009 to 2010
$6.3M
Intramural NIH HHS ZIA HL002342Intramural NIH HHS ZIA HL006105Intramural NIH HHS ZIA HL006106
6 · The paper itself

Abstract

Epstein-Barr virus (EBV)-associated postallogeneic stem cell transplantation (SCT) lymphoproliferative disorder (PTLD) is often life threatening. The risk of EBV reactivation is highest in older patients, T cell-depleted SCT (in vivo or vitro), and in unrelated or mismatched SCT. Cumulative numbers of patients with EBV reactivation and PTLD are rising as more patients at high risk for EBV reactivation and PTLD are receiving allo-SCT. Novel but easily applicable strategies are needed to prevent EBV reactivation and PTLD to serve the needs of the increasingly enlarging population of high-risk SCT recipients across the globe.

Indexed as

Antibodies, Monoclonal, Murine-DerivedAntineoplastic AgentsDNA, ViralEpstein-Barr Virus InfectionsHerpesvirus 4, HumanHumansImmunocompromised HostImmunosuppression TherapyLymphoproliferative DisordersRiskRituximabSirolimusStem Cell TransplantationT-Lymphocytes, CytotoxicTransplantation, HomologousViral LoadAntibodies, Monoclonal, Murine-DerivedAntineoplastic AgentsDNA, ViralRituximabSirolimus

Identifiers

PMID20732435
PMCPMC3763478
OpenAlexW2138786761

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.