Evidence map›Paper›PMID 20732312›Full record

ReviewBrain research2010

Using transgenic mouse models to study oxytocin's role in the facilitation of species propagation.

Heon-Jin Lee, Jerome Pagani, W Scott Young

Abstract readReview
In one paragraph

Review in Brain research, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Heon-Jin LeeDepartment of Dental Microbiology, School of Dentistry, Kyungpook National University, Daegu, South Korea.
Jerome Pagani
W Scott Young
United States Department of Health and Human Services · USKyungpook National University · KR

Funding

Roles of Oxytocin and Vasopressin in BrainZIAMH002498 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI YOUNG, WALTER SCOTT · 2009 to 2022
$26.3M
REGULATION OF GENE EXPRESSION IN THE BRAINZ01MH002498 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI YOUNG, WALTER SCOTT · 1990 to 2008
$3.2M
Intramural NIH HHS Z01 MH002498Intramural NIH HHS ZIA MH002498
6 · The paper itself

Abstract

Oxytocin and its receptor are important for a wide range of effects, from social memory to uterine contractions. It is an evolutionarily well-conserved hormone that is particularly important in social and gregarious animals. Research on small mammals has yielded a rich literature on oxytocin's many functions. Recently a new tool has been created that has furthered our understanding of oxytocin's role in behavior: transgenic mice that lack either the ability to synthesize oxytocin or the oxytocin receptor itself. The study of these lines, while still in its infancy, is already bearing fruit and offers the promise of insight into some human disorders characterized by aberrant social behavior.

Indexed as

AggressionAnimalsFemaleGonadal Steroid HormonesHumansMiceMice, KnockoutMice, TransgenicOxytocinPregnancyReceptors, OxytocinReproductionSexual Behavior, AnimalSocial BehaviorGonadal Steroid HormonesOxytocinReceptors, Oxytocin

Identifiers

PMID20732312
PMCPMC2992605
OpenAlexW2066692785

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.