ArticleEvolution; international journal of organic evolution2011
Developmental decoupling of alternative phenotypes: insights from the transcriptomes of horn-polyphenic beetles.
Article in Evolution; international journal of organic evolution, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
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40 citing papers in PubMed, 96 citations in OpenAlex.
- A development-centric perspective on pace-of-life syndromes.Evolution letters · 2025Article
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- Genetic regulators of a resource polyphenism interact to couple predatory morphology and behaviour.Proceedings. Biological sciences · 2024Article
- The Genetic Basis Underpinning Sexually Selected Traits across Different Animal Lineages: Are There Genetic Mechanisms in Common?Animals : an open access journal from MDPI · 2024Review
- Local adaptation to an altitudinal gradient: the interplay between mean phenotypic trait variation and phenotypic plasticity inbioRxiv : the preprint server for biology · 2024Article
- A Mediator subunit imparts robustness to a polyphenism decision.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Linking Molecular Mechanisms and Evolutionary Consequences of Resource Polyphenism.Frontiers in integrative neuroscience · 2022Review
- Nutrition-responsive gene expression and the developmental evolution of insect polyphenism.Nature ecology & evolution · 2020Article
- Differences in Cell Proliferation and Craniofacial Phenotype of Closely Related Species in the Pupfish Genus Cyprinodon.The Journal of heredity · 2020Article
- Molecular evolution of cytochrome C oxidase-I protein of insects living in Saudi Arabia.PloS one · 2019Article
- Morph-specific artificial selection reveals a constraint on the evolution of polyphenisms.Proceedings. Biological sciences · 2018Article
- Recent advances in understanding the mechanisms of sexually dimorphic plasticity: insights from beetle weapons and future directions.Current opinion in insect science · 2018Review
- On the Reciprocally Causal and Constructive Nature of Developmental Plasticity and Robustness.Frontiers in genetics · 2018Review
- Accelerated Evolution of Developmentally Biased Genes in the Tetraphenic Ant Cardiocondyla obscurior.Molecular biology and evolution · 2017Article
- Asymmetric interactions between doublesex and tissue- and sex-specific target genes mediate sexual dimorphism in beetles.Nature communications · 2017Article
- Caste-biased gene expression in a facultatively eusocial bee suggests a role for genetic accommodation in the evolution of eusociality.Proceedings. Biological sciences · 2017Article
- Transcriptomics of Intralocus Sexual Conflict: Gene Expression Patterns in Females Change in Response to Selection on a Male Secondary Sexual Trait in the Bulb Mite.Genome biology and evolution · 2016Article
- Hedgehog signaling enables nutrition-responsive inhibition of an alternative morph in a polyphenic beetle.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- De novo transcriptome assembly of the grapevine phylloxera allows identification of genes differentially expressed between leaf- and root-feeding forms.BMC genomics · 2016Article
- The transcriptomic basis of tissue- and nutrition-dependent sexual dimorphism in the beetle Onthophagus taurus.Ecology and evolution · 2016Article
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6 authors at 1 institution in 1 country.
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Abstract
Developmental mechanisms play an important role in determining the costs, limits, and evolutionary consequences of phenotypic plasticity. One issue central to these claims is the hypothesis of developmental decoupling, where alternate morphs result from evolutionarily independent developmental pathways. We address this assumption through a microarray study that tests whether differences in gene expression between alternate morphs are as divergent as those between sexes, a classic example of developmental decoupling. We then examine whether genes with morph-biased expression are less conserved than genes with shared expression between morphs, as predicted if developmental decoupling relaxes pleiotropic constraints on divergence. We focus on the developing horns and brains of two species of horned beetles with impressive sexual- and morph-dimorphism in the expression of horns and fighting behavior. We find that patterns of gene expression were as divergent between morphs as they were between sexes. However, overall patterns of gene expression were also highly correlated across morphs and sexes. Morph-biased genes were more evolutionarily divergent, suggesting a role of relaxed pleiotropic constraints or relaxed selection. Together these results suggest that alternate morphs are to some extent developmentally decoupled, and that this decoupling has significant evolutionary consequences. However, alternative morphs may not be as developmentally decoupled as sometimes assumed and such hypotheses of development should be revisited and refined.
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