Evidence map›Paper›PMID 20731335›Full record

ArticleLangmuir : the ACS journal of surfaces and colloids2010

Sequential layer analysis of protein immunosensors based on single wall carbon nanotube forests.

Ruchika Malhotra, Fotios Papadimitrakopoulos, James F Rusling

Abstract read
In one paragraph

Article in Langmuir : the ACS journal of surfaces and colloids, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Review
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  8. Automated 4-Sample Protein Immunoassays using 3D-Printed Microfluidics.Analytical methods : advancing methods and applications · 2018
    Article
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  11. Review
  12. Article
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  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ruchika MalhotraDepartment of Chemistry, University of Connecticut, 55 North Eagleville Road, Storrs, Connecticut 06269- 3060, USA.
Fotios Papadimitrakopoulos
James F Rusling

Funding

BIOSENSOR ARRAYS BASED ON SINGLE WALL CARBON NANOTUBESR01ES013557 · NIEHS · UNIVERSITY OF CONNECTICUT STORRS · PI RUSLING, JAMES F. · 2006 to 2010
$1.6M
NIEHS NIH HHS ES013557NIEHS NIH HHS R01 ES013557
6 · The paper itself

Abstract

Electrochemical immunosensors using vertically aligned single wall carbon nanotube (SWNT) forests can provide ultrasensitive, accurate cancer biomarker protein assays. Herein we report a systematic investigation of the structure, thickness, and functionality of each layer of these immunosensors using atomic force microscopy (AFM), quartz crystal microbalance (QCM), and scanning white light interferometry (SWLI). This provides a detailed picture of the surface morphology of each layer along with surface concentration and thickness of each protein layer. Results reveal that the major reasons for sensitivity gain can be assigned to the dense packing of carboxylated SWNT forest tips, which translate to a large surface concentration of capture antibodies, together with the high quality of conductive SWNT forests.

Indexed as

AnimalsBiosensing TechniquesCattleHumansImmunoassayInterferometryMicroscopy, Atomic ForceNanotubes, CarbonProteinsQuartz Crystal Microbalance TechniquesSpectrum Analysis, RamanSurface PropertiesNanotubes, CarbonProteins

Identifiers

PMID20731335
PMCPMC2939275

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.