ReviewWiley interdisciplinary reviews. Systems biology and medicine
Live cell imaging and systems biology.
Review in Wiley interdisciplinary reviews. Systems biology and medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 39 citations in OpenAlex.
- An antioxidant screen identifies ascorbic acid for prevention of light-induced mitotic prolongation in live cell imaging.Communications biology · 2023Article
- Review
- Trans-channel fluorescence learning improves high-content screening for Alzheimer's disease therapeutics.Nature machine intelligence · 2022Article
- ATP and spontaneous calcium oscillations control neural stem cell fate determination in Huntington's disease: a novel approach for cell clock research.Molecular psychiatry · 2021Article
- A real-time assay for cell-penetrating peptide-mediated delivery of molecular cargos.PloS one · 2021Article
- Comparison of High- and Low-LET Radiation-Induced DNA Double-Strand Break Processing in Living Cells.International journal of molecular sciences · 2020Article
- A fully-automated, robust, and versatile algorithm for long-term budding yeast segmentation and tracking.PloS one · 2019Article
- Large-scale patterning of single cells and cell clusters in hydrogels.Scientific reports · 2018Article
- Signal Distortion: How Intracellular Pathogens Alter Host Cell Fate by Modulating NF-κB Dynamics.Frontiers in immunology · 2018Review
- Dye-Doped Fluorescent Silica Nanoparticles for Live Cell and In Vivo Bioimaging.Nanomaterials (Basel, Switzerland) · 2016Review
- Genome-wide footprinting: ready for prime time?Nature methods · 2016Article
- Live-cell imaging.Cell adhesion & migration · 2014Article
- Eukaryotic transcriptional dynamics: from single molecules to cell populations.Nature reviews. Genetics · 2013Review
- Article
- Light microscopy applications in systems biology: opportunities and challenges.Cell communication and signaling : CCS · 2013Article
- Improved spatial direct method with gradient-based diffusion to retain full diffusive fluctuations.The Journal of chemical physics · 2012Article
- Interrogation of inhibitor of nuclear factor κB α/nuclear factor κB (IκBα/NF-κB) negative feedback loop dynamics: from single cells to live animals in vivo.The Journal of biological chemistry · 2012Article
- Imaging protein complex formation in the autophagy pathway: analysis of the interaction of LC3 and Atg4B(C74A) in live cells using Förster resonance energy transfer and fluorescence recovery after photobleaching.Journal of biomedical optics · 2012Article
- Functioning nanomachines seen in real-time in living bacteria using single-molecule and super-resolution fluorescence imaging.International journal of molecular sciences · 2011Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Much of the experimental data used to construct mathematical models of molecular networks are derived from in vitro measurements. However, there is increasing evidence that in vitro measurements fail to capture both the complexity and the individuality found in single, living cells. These limitations can be overcome by live cell microscopy which is evolving to enable in vivo biochemistry. Here, we survey the current capabilities of live cell microscopy and illustrate how a number of different imaging approaches could be applied to analyze a specific molecular network. We argue that incorporation of such quantitative live-cell imaging methods is critical for the progress of systems biology.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.