ArticleCerebellum (London, England)2010
Inferior olive response to passive tactile and visual stimulation with variable interstimulus intervals.
Article in Cerebellum (London, England), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Developmentally Unique Cerebellar Processing Prioritizes Self- over Other-Generated Movements.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Developmentally unique cerebellar processing prioritizes self-over other-generated movements.bioRxiv : the preprint server for biology · 2024Article
- Role of the dorsolateral prefrontal cortex in processing temporal anomalies retained in working memory.Frontiers in behavioral neuroscience · 2024Article
- The time squares sequences: a new task for assessing visuospatial working memory.Frontiers in behavioral neuroscience · 2023Article
- Cerebellum-Cortical Interaction in Spatial Navigation and Its Alteration in Dementias.Brain sciences · 2022Review
- How Does the Central Nervous System for Posture and Locomotion Cope With Damage-Induced Neural Asymmetry?Frontiers in systems neuroscience · 2022Review
- The Brainstem-Informed Autism Framework: Early Life Neurobehavioral Markers.Frontiers in integrative neuroscience · 2021Article
- An Opponent Process Cerebellar Asymmetry for Regulating Word Association Priming.Cerebellum (London, England) · 2019Article
- Neural Network of Predictive Motor Timing in the Context of Gender Differences.Neural plasticity · 2016Article
- Consensus paper: the role of the cerebellum in perceptual processes.Cerebellum (London, England) · 2015Review
- Signals and learning rules guiding oculomotor plasticity.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Article
- Cerebellar processing of sensory inputs primes motor cortex plasticity.Cerebral cortex (New York, N.Y. : 1991) · 2013Article
- Anti-malaria drug mefloquine induces motor learning deficits in humans.Frontiers in neuroscience · 2010Article
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Authors and funding
5 authors.
Funding
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Abstract
The unique anatomical and electrophysiological features of the inferior olive and its importance to cerebellar function have been recognized for decades. However, understanding the exact function of the inferior olive has been limited by the general lack of correlation between its neural activity and specific behavioral states. Electrophysiological studies in animals showed that the inferior olive response to sensory stimuli is generally invariant to stimulus properties but is enhanced by unexpected stimuli. Using functional magnetic resonance imaging in humans, we have shown that the inferior olive is activated when subjects performed a task requiring perception of visual stimuli with unpredictable timing (Xu et al. J Neurosci 26(22):5990-5995, 2006, Liu et al. J Neurophysiol 100(3):1557-1561, 2008). In the current study, subjects were scanned while passively perceiving visual and tactile stimuli that were rendered unpredictable by continuously varying interstimulus intervals (ISIs). Sequences of visual stimuli and tactile stimuli to the right hand were presented separately within the same scanning session. In addition to the activation of multiple areas in the cerebellar cortex consistent with previous imaging studies, the results show that both tactile and visual stimulation with variable ISIs were effective in activating the inferior olive. Together with our previous findings, the current results are consistent with the electrophysiological studies in animals and further support the view that the inferior olive and the climbing fiber system primarily convey the temporal information of sensory input regardless of the modality.
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