ArticleJournal of molecular evolution2010
Sexual selection and the molecular evolution of ADAM proteins.
Article in Journal of molecular evolution, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 44 citations in OpenAlex.
- Sperm competition intensity shapes divergence in both sperm morphology and reproductive genes across murine rodents.Evolution; international journal of organic evolution · 2024Article
- Convergent rates of protein evolution identify novel targets of sexual selection in primates.Evolution; international journal of organic evolution · 2024Article
- Rapid divergence of a gamete recognition gene promoted macroevolution of Eutheria.Genome biology · 2022Article
- The Importance of Gene Duplication and Domain Repeat Expansion for the Function and Evolution of Fertilization Proteins.Frontiers in cell and developmental biology · 2022Review
- Nonadaptive molecular evolution of seminal fluid proteins in Drosophila.Evolution; international journal of organic evolution · 2021Article
- Epigenomic profiling of primate lymphoblastoid cell lines reveals the evolutionary patterns of epigenetic activities in gene regulatory architectures.Nature communications · 2021Article
- Reproductive Proteins Evolve Faster Than Non-reproductive Proteins AmongFrontiers in plant science · 2021Article
- Evolutionary analysis of genes coding for Cysteine-RIch Secretory Proteins (CRISPs) in mammals.BMC evolutionary biology · 2020Article
- Endless forms of sexual selection.PeerJ · 2019Article
- LMAP: Lightweight Multigene Analyses in PAML.BMC bioinformatics · 2016Article
- Selective constraints on protamine 2 in primates and rodents.BMC evolutionary biology · 2016Article
- Article
- Sexual selection and the adaptive evolution of PKDREJ protein in primates and rodents.Molecular human reproduction · 2015Article
- Sexual selection on protamine and transition nuclear protein expression in mouse species.Proceedings. Biological sciences · 2014Article
- Structural evolution of CatSper1 in rodents is influenced by sperm competition, with effects on sperm swimming velocity.BMC evolutionary biology · 2014Article
- Rates of evolution of hominoid seminal proteins are correlated with function and expression, rather than mating system.Journal of molecular evolution · 2014Article
- Proteins involved in motility and sperm-egg interaction evolve more rapidly in mouse spermatozoa.PloS one · 2014Article
- The Rhesus macaque (Macaca mulatta) sperm proteome.Molecular & cellular proteomics : MCP · 2013Article
- Positive selection in the adhesion domain of Mus sperm Adam genes through gene duplications and function-driven gene complex formations.BMC evolutionary biology · 2013Article
- Selection on the Drosophila seminal fluid protein Acp62F.Ecology and evolution · 2013Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rapid evolution has been identified for many reproductive genes and recent studies have combined phylogenetic tests and information on species mating systems to test sexual selection. Here we examined the molecular evolution of the ADAM gene family, a diverse group of 35 proteins capable of adhesion to and cleavage of other proteins, using sequence data from 25 mammalian genes. Out of the 25 genes analyzed, all those expressed in male reproductive tissue showed evidence of positive selection. Positively selected amino acids within the protein adhesion domain were only found in sperm surface ADAM proteins (ADAMs 1, 2, 3, 4, and 32) suggesting selection driven by male x female interactions. We tested heterogeneity in rates of evolution of the adhesion domain of ADAM proteins by using sequence data from Hominidae and macaques. The use of the branch and branch-site models (PAML) showed evidence of higher d (N)/d (S) and/or positive selection linked to branches experiencing high postmating selective pressures (chimpanzee and macaque) for Adams 2, 18, and 23. Moreover, we found consistent higher proportion of nonsynonymous relative to synonymous and noncoding sequence substitutions in chimpanzee and/or macaque only for Adams 2, 18, and 23. Our results suggest that lineage-specific sexual selection bouts might have driven the evolution of the adhesion sperm protein surface domains of ADAMs 2 and 18 in primates. Adams 2 and 18 are localized in chromosome 8 of primates and adjacent to each other, so their evolution might have also been influenced by their common genome localization.
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