Evidence map›Paper›PMID 20730508›Full record

ReviewTheory in biosciences = Theorie in den Biowissenschaften2011

Using views of Systems Biology Cloud: application for model building.

Oliver Ruebenacker, Michael Blinov

Abstract readReview
PubMed Publisher
In one paragraph

Review in Theory in biosciences = Theorie in den Biowissenschaften, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Emerging modelling methodologies in medicine and biology, Introduction to the special issue.Theory in biosciences = Theorie in den Biowissenschaften · 2011
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Oliver RuebenackerCenter for Cell Analysis and Modeling, University of Connecticut Health Center, Farmington, CT, USA.
Michael Blinov

Funding

VIRTUAL FCSP41RR013186 · NCRR · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI SABATINI, BERNARDO L · 1998 to 2011
$14.2M
POLARITY IN NETWORKS AND PATHWAYS(RMI)U54RR022232 · NCRR · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI LOEW, LESLIE M · 2005 to 2009
$12.9M
COMPUTATIONAL TOOLS FOR RULE-BASED MODELING OF BIOCHEMICAL SYSTEMSR01GM076570 · NIGMS · UNIVERSITY OF NEW MEXICO · PI HLAVACEK, WILLIAM S · 2007 to 2009
$815k
NCRR NIH HHS P41 RR013186NCRR NIH HHS U54 RR022232NIGMS NIH HHS R01 GM076570
6 · The paper itself

Abstract

A large and growing network ("cloud") of interlinked terms and records of items of Systems Biology knowledge is available from the web. These items include pathways, reactions, substances, literature references, organisms, and anatomy, all described in different data sets. Here, we discuss how the knowledge from the cloud can be molded into representations (views) useful for data visualization and modeling. We discuss methods to create and use various views relevant for visualization, modeling, and model annotations, while hiding irrelevant details without unacceptable loss or distortion. We show that views are compatible with understanding substances and processes as sets of microscopic compounds and events respectively, which allows the representation of specializations and generalizations as subsets and supersets respectively. We explain how these methods can be implemented based on the bridging ontology Systems Biological Pathway Exchange (SBPAX) in the Systems Biology Linker (SyBiL) we have developed.

Indexed as

Databases, FactualInternetModels, BiologicalSoftwareSystems Biology

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.