Evidence map›Paper›PMID 20730381›Full record

ReviewTheScientificWorldJournal2010

Integrated brain circuits: neuron-astrocyte interaction in sleep-related rhythmogenesis.

Michael M Halassa, Marco Dal Maschio, Riccardo Beltramo, Philip G Haydon, Fabio Benfenati, Tommaso Fellin

Open access · goldAbstract readReview
In one paragraph

Review in TheScientificWorldJournal, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Neuronal transgene expression in dominant-negative SNARE mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014
    Article
  9. Article
  10. Article
  11. In vivo stimulus-induced vasodilation occurs without IP3 receptor activation and may precede astrocytic calcium increase.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Michael M HalassaDepartment of Psychiatry, Massachusetts General Hospital, Boston, MA, USA. mhalassa@partners.org
Marco Dal Maschio
Riccardo Beltramo
Philip G Haydon
Fabio Benfenati
Tommaso Fellin
Italian Institute of Technology · ITMcLean Hospital · USTufts University · US

Funding

ASTROCYTE/NEURON SIGNALINGR01NS037585 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI HAYDON, PHILIP G · 1998 to 2019
$4.5M
NINDS NIH HHS R01 NS037585Telethon GGP09134
6 · The paper itself

Abstract

Although astrocytes are increasingly recognized as important modulators of neuronal excitability and information transfer at the synapse, whether these cells regulate neuronal network activity has only recently started to be investigated. In this article, we highlight the role of astrocytes in the modulation of circuit function with particular focus on sleep-related rhythmogenesis. We discuss recent data showing that these glial cells regulate slow oscillations, a specific thalamocortical activity that characterizes non-REM sleep, and sleep-associated behaviors. Based on these findings, we predict that our understanding of the genesis and tuning of thalamocortical rhythms will necessarily go through an integrated view of brain circuits in which non-neuronal cells can play important neuromodulatory roles.

Indexed as

AnimalsAstrocytesBrainCell CommunicationHumansModels, NeurologicalNeuronsSleepSynapses

Identifiers

PMID20730381
PMCPMC3097528
OpenAlexW1551569698

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.