Evidence map›Paper›PMID 20728887›Full record

ArticleAtherosclerosis2010

Common clinical practice versus new PRIM score in predicting coronary heart disease risk.

Ruth Frikke-Schmidt, Anne Tybjærg-Hansen, Peter Schnohr, Gorm B Jensen, Børge G Nordestgaard

Abstract readComparative Study
In one paragraph

Article in Atherosclerosis, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Development and validation of a clinical score for predicting risk of adenoma at screening colonoscopy.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2015
    Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ruth Frikke-SchmidtDepartment of Clinical Biochemistry, Rigshospitalet, Denmark. ruth.frikke-schmidt@rh.regionh.dk
Anne Tybjærg-Hansen
Peter Schnohr
Gorm B Jensen
Børge G Nordestgaard

Funding

Variable DNA sites predicting interindividual variation in health measuresP50GM065509 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SING, CHARLES · 2001 to 2011
$27.5M
Modeling DNA Diversity in Reverse Cholesterol TransportR01HL072905 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SING, CHARLES · 2003 to 2012
$5.3M
NHLBI NIH HHS HL072905NHLBI NIH HHS R01 HL072905NIGMS NIH HHS GM065509NIGMS NIH HHS P50 GM065509
6 · The paper itself

Abstract

objectivesTo compare the new Patient Rule Induction Method (PRIM) Score and common clinical practice with the Framingham Point Score for classification of individuals with respect to coronary heart disease (CHD) risk. METHODS AND

resultsPRIM Score and the Framingham Point Score were estimated for 11,444 participants from the Copenhagen City Heart Study. Gender specific cumulative incidences and 10 year absolute CHD risks were estimated for subsets defined by age, total cholesterol, high-density lipoprotein (HDL) cholesterol, blood pressure, diabetes and smoking categories. PRIM defined seven mutually exclusive subsets in women and men, with cumulative incidences of CHD from 0.01 to 0.22 in women, and from 0.03 to 0.26 in men. PRIM versus Framingham Point Score found 11% versus 4% of all women, and 31% versus 35% of all men to have 10 year CHD risks>20%. Among women ≥ 65 years with hypertension and/or with diabetes, 10 year CHD risk>20% was found for 100% with PRIM scoring but for only 18% with the Framingham Point Score.

conclusionCompared to the PRIM Score, common clinical practice with the Framingham Point Score underestimates CHD risk in women, especially in women≥65 years with hypertension and/or with diabetes.

Indexed as

AdultAgedAged, 80 and overBlood PressureCholesterolCholesterol, HDLCoronary DiseaseDenmarkDiabetes ComplicationsFemaleHumansHypertensionMaleMiddle AgedRisk AssessmentRisk FactorsCholesterolCholesterol, HDL

Identifiers

PMID20728887
PMCPMC3117128

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.