ArticleThe Journal of urology2010
Inaccurate reporting of mineral composition by commercial stone analysis laboratories: implications for infection and metabolic stones.
Article in The Journal of urology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- Metabolic diagnosis and medical prevention of calcium nephrolithiasis and its systemic manifestations: a consensus statement.Journal of nephrology · 2016Guideline
- Improved 24-hour urine parameters associated with reduced symptomatic kidney stone recurrence.Urolithiasis · 2025Article
- Investigation and quantification of composition variability in urinary stone analysis.Investigative and clinical urology · 2024Article
- Advancements in stone classification: unveiling the beauty of urolithiasis.World journal of urology · 2024Review
- Sample preparation and analysis protocols for the elucidation of structure and chemical distribution in kidney stones.Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy · 2024Article
- Machine Learning Prediction of Kidney Stone Composition Using Electronic Health Record-Derived Features.Journal of endourology · 2022Article
- Urine and stone analysis for the investigation of the renal stone former: a consensus conference.Urolithiasis · 2021Article
- Using micro computed tomographic imaging for analyzing kidney stones.Comptes rendus. Chimie (Print) · 2021Article
- The surgeon's role on chemical investigations of the composition of urinary stones.Urolithiasis · 2020Article
- Variability in stone composition and metabolic correlation between kidneys in patients with bilateral nephrolithiasis.International urology and nephrology · 2020Article
- Metabolic evaluation and medical management of staghorn calculi.Asian journal of urology · 2020Review
- Performance of a Natural Language Processing Method to Extract Stone Composition From the Electronic Health Record.Urology · 2019Article
- Association Between Randall's Plaque Stone Anchors and Renal Papillary Pits.Journal of endourology · 2019Article
- Interpreting the results of chemical stone analysis in the era of modern stone analysis techniques.Journal of nephrology · 2017Article
- Integration and utilization of modern technologies in nephrolithiasis research.Nature reviews. Urology · 2016Review
- Dual-Energy CT for Quantification of Urinary Stone Composition in Mixed Stones: A Phantom Study.AJR. American journal of roentgenology · 2016Article
- Novel Methods of Determining Urinary Calculi Composition: Petrographic Thin Sectioning of Calculi and Nanoscale Flow Cytometry Urinalysis.Scientific reports · 2016Article
- Quality Assessment of Urinary Stone Analysis: Results of a Multicenter Study of Laboratories in Europe.PloS one · 2016Article
- Polyisobutylene Urolithiasis Due to Ileal Conduit Urostomy Appliance: An Index Case.Journal of endourology case reports · 2015Article
- Impact of urinary stone volume on computed tomography stone attenuations measured in Hounsfield units in a large group of Austrian patients with urolithiasis.Central European journal of urology · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
purposeWe determined the accuracy of stone composition analysis at commercial laboratories. MATERIALS AND
methodsA total of 25 human renal stones with infrared spectroscopy determined composition were fragmented into aliquots and studied with micro computerized tomography to ensure fragment similarity. Representative fragments of each stone were submitted to 5 commercial stone laboratories for blinded analysis.
resultsAll laboratories agreed on the composition of 6 pure stones. Only 2 of 4 stones (50%) known to contain struvite were identified as struvite at all laboratories. Struvite was reported as a component by some laboratories for 4 stones previously determined not to contain struvite. Overall there was disagreement regarding struvite in 6 stones (24%). For 9 calcium oxalate stones all laboratories reported some mixture of calcium oxalate but the quantity of subtypes differed significantly among laboratories. In 6 apatite containing stones apatite was missed by the laboratories in 20% of samples. None of the laboratories identified atazanavir in a stone containing that antiviral drug. One laboratory reported protein in every sample while all others reported it in only 1. Nomenclature for apatite differed among laboratories with 1 reporting apatite as carbonate apatite and never hydroxyapatite, another never reporting carbonate apatite and always reporting hydroxyapatite, and a third reporting carbonate apatite as apatite with calcium carbonate.
conclusionsCommercial laboratories reliably recognize pure calculi. However, variability in the reporting of mixed calculi suggests a problem with the accuracy of stone analysis results. There is also a lack of standard nomenclature used by laboratories.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.