ArticleAmerican journal of hypertension2011
Adult hypertension is associated with blood pressure variability in childhood in blacks and whites: the bogalusa heart study.
Article in American journal of hypertension, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00005129 (The Bogalusa Heart Study), which is not on this map. Cited by 34 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Bogalusa Heart Study
Who cites it
34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 60 citations in OpenAlex.
- Effect of passive exposure to cigarette smoke on blood pressure in children and adolescents: a meta-analysis of epidemiologic studies.BMC pediatrics · 2019Pooled it
- The influence of early-life conditions on cardiovascular disease later in life among ethnic minority populations: a systematic review.Internal and emergency medicine · 2016Pooled it
- Blood pressure variability and cardiovascular risk in pediatric hypertension.Pediatric nephrology (Berlin, Germany) · 2026Article
- Ambulatory blood pressure variability in prediction of target organ injury: the SHIP AHOY study.Pediatric nephrology (Berlin, Germany) · 2026Article
- Cardiovascular variability, sociodemographics, and biomarkers of disease: the MIDUS study.Frontiers in physiology · 2023Article
- Is there a characteristic pattern of ambulatory blood pressure profile in type 1 diabetic children and adolescents?Annals of pediatric endocrinology & metabolism · 2022Article
- Treatment of congenital adrenal hyperplasia in children aged 0-3 years: a retrospective multicenter analysis of salt supplementation, glucocorticoid and mineralocorticoid medication, growth and blood pressure.European journal of endocrinology · 2022Article
- Joint Modeling of Individual Trajectories, Within-Individual Variability, and a Later Outcome: Systolic Blood Pressure Through Childhood and Left Ventricular Mass in Early Adulthood.American journal of epidemiology · 2021Article
- School-based surveillance on visit-to-visit blood pressure variability and high blood pressure in children and adolescents.BMC cardiovascular disorders · 2021Article
- Article
- Hypertensive Measures In Schoolchildren: Risk Of Central Obesity And Protective Effect Of Moderate-To-Vigorous Physical Activity.Arquivos brasileiros de cardiologia · 2020Article
- Augmented resting beat-to-beat blood pressure variability in young, healthy, non-Hispanic black men.Experimental physiology · 2020Article
- Anthropometric indicators associated with high blood pressure in children living in urban and rural areas.Revista latino-americana de enfermagem · 2019Article
- Visit-to-visit blood pressure variability in children and adolescents with renal disease.Clinical and experimental nephrology · 2018Article
- Cumulative Incidence of Hypertension by 55 Years of Age in Blacks and Whites: The CARDIA Study.Journal of the American Heart Association · 2018Article
- Exaggerated Vasoconstriction to Spontaneous Bursts of Muscle Sympathetic Nerve Activity in Healthy Young Black Men.Hypertension (Dallas, Tex. : 1979) · 2018Article
- Race and Sex Differences of Long-Term Blood Pressure Profiles From Childhood and Adult Hypertension: The Bogalusa Heart Study.Hypertension (Dallas, Tex. : 1979) · 2017Article
- Blood pressure (BP) assessment-from BP level to BP variability.Pediatric nephrology (Berlin, Germany) · 2016Review
- High Blood Pressure in Adolescents of Curitiba: Prevalence and Associated Factors.Arquivos brasileiros de cardiologia · 2016Article
- Gender differences in developmental programming of cardiovascular diseases.Clinical science (London, England : 1979) · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 2 countries.
Funding
Abstract
backgroundBlood pressure (BP) is a variable physiological parameter in health and disease. Increased BP variability over time in adults is associated with severity of end-organ damage and a higher rate of cardiovascular events, even after adjusting for the mean levels. This study tested the hypothesis that childhood BP variability, besides the mean levels, is also predictive of adulthood hypertension.
methodsThe study cohort consisted of 1,797 subjects (1,091 whites and 706 blacks; age = 21-48 years) enrolled in the Bogalusa Heart Study since childhood. BP variability was depicted as s.d. of 4-8 serial measurements in childhood.
resultsBlacks showed significantly greater childhood systolic BP (SBP) variability than whites. In multivariable logistic regression analyses, adjusting for race, sex, mean childhood age, s.d. of childhood body mass index (BMI), mean childhood BP levels, adulthood age and BMI, adult hypertension was significantly associated with s.d. of childhood SBP (odds ratio (OR) (95% confidence intervals) = 1.28 (1.09, 1.51), P = 0.002) and s.d. of childhood diastolic BP (DBP; 1.36 (1.16, 1.58), P < 0.001). When using adulthood BP levels as continuous dependent variables in linear regression models, adjusting for the same covariates, adulthood SBP and DBP levels were significantly associated with s.d. of childhood SBP (standardized regression coefficient β = 0.086, P < 0.001) and s.d. of childhood DBP (β = 0.105, P < 0.001), respectively.
conclusionsIncreases in BP variations as well as levels in early life are predictive of adult hypertension, which underscore the childhood origin of the natural history of essential hypertension.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.