ArticleNature2010
Trans-acting small RNA determines dominance relationships in Brassica self-incompatibility.
Article in Nature, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers.
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Who cites it
74 citing papers in PubMed, 162 citations in OpenAlex.
- From recognition to response: integrated signaling pathways determining pollen acceptance and rejection in Brassicaceae.The New phytologist · 2026Review
- Dominance modifiers at the Arabidopsis self-incompatibility locus retain proto-miRNA features and act through non-canonical pathways.PLoS genetics · 2026Article
- Evolution of dominance in a Mendelian trait is linked to the evolution of environmental plasticity.Evolution; international journal of organic evolution · 2026Article
- Distinct haplotypes and reversed dominance at a single-gene balanced polymorphism controlling heterodichogamy in two genera of wingnuts.Current biology : CB · 2025Article
- Self-sterility, self-incompatibility and xenia: a review of the mechanisms of cross-pollination benefits in animal-pollinated crops.Annals of botany · 2025Review
- A Balanced Inversion Polymorphism Exhibits a Dominance Reversal at the Gene Expression Level that Depends on Developmental Context.Molecular biology and evolution · 2025Article
- Molecular mechanisms and genetic regulation of self-incompatibility in flowering plants: implications for crop improvement and evolutionary biology.Plant molecular biology · 2025Review
- Evolution of dominance in a Mendelian trait is linked to the evolution of environmental plasticity.bioRxiv : the preprint server for biology · 2025Article
- Dominance between self-incompatibility alleles determines the mating system ofEvolution letters · 2024Article
- Complementing model species with model clades.The Plant cell · 2024Review
- Molecular insights into self-incompatibility systems: From evolution to breeding.Plant communications · 2024Review
- Molecular mechanisms of self-incompatibility in Brassicaceae and Solanaceae.Proceedings of the Japan Academy. Series B, Physical and biological sciences · 2024Review
- Fine mapping and identification of the bright green leaf geneFrontiers in plant science · 2024Article
- Dominance in self-compatibility between subgenomes of allopolyploid Arabidopsis kamchatica shown by transgenic restoration of self-incompatibility.Nature communications · 2023Article
- Stop and go signals at the stigma-pollen interface of the Brassicaceae.Plant physiology · 2023Article
- MLPK function is not required for self-incompatibility in the SPlant reproduction · 2023Article
- Transition to Self-compatibility Associated With Dominant S-allele in a Diploid Siberian Progenitor of Allotetraploid Arabidopsis kamchatica Revealed by Arabidopsis lyrata Genomes.Molecular biology and evolution · 2023Article
- Genetic Mechanisms for Hybrid Breeding in Vegetable Crops.Plants (Basel, Switzerland) · 2023Review
- Article
- Ancestral self-compatibility facilitates the establishment of allopolyploids in Brassicaceae.Plant reproduction · 2023Review
14 more citing papers are in PubMed but not listed here.
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A diploid organism has two copies of each gene, one inherited from each parent. The expression of two inherited alleles is sometimes biased by the effects known as dominant/recessive relationships, which determine the final phenotype of the organism. To explore the mechanisms underlying these relationships, we have examined the monoallelic expression of S-locus protein 11 genes (SP11), which encode the male determinants of self-incompatibility in Brassica. We previously reported that SP11 expression was monoallelic in some S heterozygotes, and that the promoter regions of recessive SP11 alleles were specifically methylated in the anther tapetum. Here we show that this methylation is controlled by trans-acting small non-coding RNA (sRNA). We identified inverted genomic sequences that were similar to the recessive SP11 promoters in the flanking regions of dominant SP11 alleles. These sequences were specifically expressed in the anther tapetum and processed into 24-nucleotide sRNA, named SP11 methylation inducer (Smi). Introduction of the Smi genomic region into the recessive S homozygotes triggered the methylation of the promoter of recessive SP11 alleles and repressed their transcription. This is an example showing sRNA encoded in the flanking region of a dominant allele acts in trans to induce transcriptional silencing of the recessive allele. Our finding may provide new insights into the widespread monoallelic gene expression systems.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.