Evidence map›Paper›PMID 20724682›Full record

ArticleAmerican journal of public health2010

Antiretroviral therapy as HIV prevention: status and prospects.

Kenneth H Mayer, Kartik K Venkatesh

Abstract read
In one paragraph

Article in American journal of public health, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 3 pooled it
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 3 syntheses or guidelines pooled it, 100 citations in OpenAlex.

  1. Pooled it
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  4. Trial
  5. Project enhance: a randomized controlled trial of an individualized HIV prevention intervention for HIV-infected men who have sex with men conducted in a primary care setting.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2013
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Kenneth H MayerAlpert Medical School, Brown University, Providence, RI, USA. Kenneth_Mayer@brown.edu
Kartik K Venkatesh
Brown University · US

Funding

Translational ScienceP30AI042853 · NIAID · MIRIAM HOSPITAL · PI LARRY K BROWN · 1998 to 2026
$51.7M
Clinical Trial Unit for HIV Prevention and Microbicide ResearchU01AI069480 · NIAID · FENWAY COMMUNITY HEALTH CENTER · PI MAYER, KENNETH H · 2008 to 2011
$7.3M
Clinical Trial Unit for HIV Prevention and Microbicide ResearchUM1AI069480 · NIAID · FENWAY COMMUNITY HEALTH CENTER · PI MAYER, KENNETH H · 2012 to 2014
$2.3M
NIAID NIH HHS 5U01AI06948NIAID NIH HHS P30 AI042853NIAID NIH HHS P30 AI42853NIAID NIH HHS U01 AI069480NIAID NIH HHS UM1 AI069480
6 · The paper itself

Abstract

As antiretroviral treatment of HIV infection has become increasingly accessible, attention has focused on whether these drugs can used for prevention because of increased tolerability of newer medications, decreased cost, and the limitations of other approaches. We review the status of antiretroviral HIV prevention, including chemoprophylaxis, as well as the effects of treatment of infected individuals on prevention. It is possible that the life-saving agents that have transformed the natural history of AIDS can be a critical component of HIV prevention efforts, but their ultimate role in affecting HIV transmission dynamics remains to be defined.

Indexed as

Anti-Retroviral AgentsAntiretroviral Therapy, Highly ActiveChemopreventionDisease OutbreaksFemaleGlobal HealthHealth BehaviorHealth PolicyHIV InfectionsHumansMalePost-Exposure ProphylaxisPrimary PreventionAnti-Retroviral Agents

Identifiers

PMID20724682
PMCPMC2936983
OpenAlexW2038342867

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.