Evidence map›Paper›PMID 20724677›Full record

ArticleAmerican journal of public health2010

Smoking-related health risks among persons with HIV in the Strategies for Management of Antiretroviral Therapy clinical trial.

Alan R Lifson, Jacqueline Neuhaus, Jose Ramon Arribas, Mary van den Berg-Wolf, Ann M Labriola, Timothy R H Read, INSIGHT SMART Study Group

2 registry-linked trialsAbstract read
In one paragraph

Article in American journal of public health, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 184 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
184citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02898597 nacompletednot on this mapstarted 2016, after this paper: background citation

Smoking Cessation Intervention for Women With HIV/AIDS

TypeinterventionalSponsorUniversity of Massachusetts, BostonRan2016 to 2018Enrolled49ConditionsAIDS/HIVArmsCognitive Behavioral Therapy
NCT05487807 phase1recruitingnot on this mapstarted 2023, after this paper: background citation

Quit4Life+: Adapting and Evaluating a Phone-Based Tobacco Use Cessation Program for People Living With HIV in Uganda and Zambia (Quit4Life+ )

TypeinterventionalSponsorUniversity of Southern CaliforniaRan2023 to 2026Enrolled800ConditionsNicotine Dependence, Tobacco DependenceArmsNicotine patch, text messaging
3 · Its place in the literature

Who cites it

184 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Interventions for tobacco use cessation in people living with HIV.The Cochrane database of systematic reviews · 2024
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Interventions for tobacco use cessation in people living with HIV and AIDS.The Cochrane database of systematic reviews · 2016
    Pooled it
  5. Smoking-cessation interventions in people living with HIV infection: a systematic review.The Journal of the Association of Nurses in AIDS Care : JANAC
    Pooled it
  6. Trial
  7. Trial
  8. Trial
  9. Trial
  10. Trial
  11. Trial
  12. Outcomes of a Tailored Intervention for Cigarette Smoking Cessation Among Latinos Living With HIV/AIDS.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2015
    Trial
  13. Trial
  14. Trial
  15. Trial
  16. Long-term outcomes of a cell phone-delivered intervention for smokers living with HIV/AIDS.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2013
    Trial
  17. Trial
  18. Safety of varenicline among smokers enrolled in the lung HIV study.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2013
    Trial
  19. Trial
  20. Efficacy of cell phone-delivered smoking cessation counseling for persons living with HIV/AIDS: 3-month outcomes.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2012
    Trial

124 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alan R LifsonDivision of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN 55454-1015, USA. lifso001@umn.edu
Jacqueline Neuhaus
Jose Ramon Arribas
Mary van den Berg-Wolf
Ann M Labriola
Timothy R H Read
INSIGHT SMART Study Group

Funding

International Network for Strategic Initiatives in Global HIV Trials (INSIGHT)U01AI068641 · NIAID · UNIVERSITY OF MINNESOTA · PI NEATON, JAMES DENNIS · 2006 to 2010
$120.1M
COMMUNITY PROGRAMS FOR CLINICAL RESEARCH ON AIDSU01AI046362 · NIAID · SOCIAL AND SCIENTIFIC SYSTEMS, INC. · PI GORDIN, FRED M · 2000 to 2006
$75.9M
TERRY BEIRN COMMUNITY PROGRAMS FOR CLINICAL RESEARCH ONU01AI042170 · NIAID · UNIVERSITY OF MINNESOTA TWIN CITIES · PI NEATON, JAMES DENNIS · 1997 to 2006
$23.2M
Medical Research Council MC_U122886352NIAID NIH HHS U01 AI042170NIAID NIH HHS U01-AI042170NIAID NIH HHS U01 AI046362NIAID NIH HHS U01 AI068641NIAID NIH HHS U01-AI068641NIAID NIH HHS U01-AI46362
6 · The paper itself

Abstract

objectivesWe sought to determine smoking-related hazard ratios (HRs) and population-attributable risk percentage (PAR%) for serious clinical events and death among HIV-positive persons, whose smoking prevalence is higher than in the general population.

methodsFor 5472 HIV-infected persons enrolled from 33 countries in the Strategies for Management of Antiretroviral Therapy clinical trial, we evaluated the relationship between baseline smoking status and development of AIDS-related or serious non-AIDS events and overall mortality.

resultsAmong all participants, 40.5% were current smokers and 24.8% were former smokers. Adjusted HRs were higher for current than for never smokers for overall mortality (2.4; P < .001), major cardiovascular disease (2.0; P = .002), non-AIDS cancer (1.8; P = .008), and bacterial pneumonia (2.3; P < .001). Adjusted HRs also were significantly higher for these outcomes among current than among former smokers. The PAR% for current versus former and never smokers combined was 24.3% for overall mortality, 25.3% for major cardiovascular disease, 30.6% for non-AIDS cancer, and 25.4% for bacterial pneumonia.

conclusionsSmoking contributes to substantial morbidity and mortality in this HIV-infected population. Providers should routinely integrate smoking cessation programs into HIV health care.

Indexed as

Antiretroviral Therapy, Highly ActiveAdultClinical Trials as TopicFemaleHIV InfectionsHumansKaplan-Meier EstimateLung NeoplasmsMaleMiddle AgedPrevalenceProspective StudiesRiskSkin NeoplasmsSmoking

Identifiers

PMID20724677
PMCPMC2936972

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.