Evidence map›Paper›PMID 20724311›Full record

GuidelineAnnals of the rheumatic diseases2011

Multinational evidence-based recommendations on how to investigate and follow-up undifferentiated peripheral inflammatory arthritis: integrating systematic literature research and expert opinion of a broad international panel of rheumatologists in the 3E Initiative.

P Machado, I Castrejon, W Katchamart, R Koevoets, B Kuriya, M Schoels, L Silva-Fernández, K Thevissen, W Vercoutere, E Villeneuve and 22 more

Open access · bronzeAbstract readConsensus StatementPractice Guideline
In one paragraph

Guideline in Annals of the rheumatic diseases, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 3 pooled it
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 72 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Pre-rheumatoid arthritis and its prevention.European journal of rheumatology · 2017
    Review
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
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  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

32 authors at 20 institutions in 19 countries.

P MachadoDepartment of Rheumatology, Coimbra University Hospital, Coimbra, Portugal. pedrommcmachado@gmail.com
I Castrejon
W Katchamart
R Koevoets
B Kuriya
M Schoels
L Silva-Fernández
K Thevissen
W Vercoutere
E Villeneuve
D Aletaha
L Carmona
R Landewé
D van der Heijde
J W J Bijlsma
V Bykerk
H Canhão
A I Catrina
P Durez
C J Edwards
M D Mjaavatten
B F Leeb
B Losada
E M Martín-Mola
P Martinez-Osuna
C Montecucco
U Müller-Ladner
M Østergaard
B Sheane
R M Xavier
J Zochling
C Bombardier
Mount Sinai Hospital · CALeiden University Medical Center · NLMaastricht University · NLAtrium Medisch Centrum Parkstad · NLCliniques Universitaires Saint-Luc · BEDiakonhjemmet Hospital · NOHospital Clínico Universitario de Caracas · VEHospital de Clínicas de Porto Alegre · BRHospital Médica Sur · MXHospital Universitario de La Princesa · ESHospital Universitario La Paz · ESHospital Universitario Puerta de Hierro Majadahonda · ESHvidovre Hospital · DKIstituti di Ricovero e Cura a Carattere Scientifico · ITKarolinska University Hospital · SEKerckhoff Klinik · DEKlinik Hietzing · ATMedical University of Vienna · ATNIHR Leeds Musculoskeletal Biomedical Research Unit · GBSociedad Española de Reumatología · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo develop evidence-based recommendations on how to investigate and follow-up undifferentiated peripheral inflammatory arthritis (UPIA).

methods697 rheumatologists from 17 countries participated in the 3E (Evidence, Expertise, Exchange) Initiative of 2008-9 consisting of three separate rounds of discussions and modified Delphi votes. In the first round 10 clinical questions were selected. A bibliographic team systematically searched Medline, Embase, the Cochrane Library and ACR/EULAR 2007-2008 meeting abstracts. Relevant articles were reviewed for quality assessment, data extraction and synthesis. In the second round each country elaborated a set of national recommendations. Finally, multinational recommendations were formulated and agreement among the participants and the potential impact on their clinical practice was assessed.

resultsA total of 39,756 references were identified, of which 250 were systematically reviewed. Ten multinational key recommendations about the investigation and follow-up of UPIA were formulated. One recommendation addressed differential diagnosis and investigations prior to establishing the operational diagnosis of UPIA, seven recommendations related to the diagnostic and prognostic value of clinical and laboratory assessments in established UPIA (history and physical examination, acute phase reactants, autoantibodies, radiographs, MRI and ultrasound, genetic markers and synovial biopsy), one recommendation highlighted predictors of persistence (chronicity) and the final recommendation addressed monitoring of clinical disease activity in UPIA.

conclusionsTen recommendations on how to investigate and follow-up UPIA in the clinical setting were developed. They are evidence-based and supported by a large panel of rheumatologists, thus enhancing their validity and practical use.

Indexed as

ArthritisArthritis, RheumatoidBiomarkersDiagnosis, DifferentialEvidence-Based MedicineHumansInternational CooperationLong-Term CarePrognosisSeverity of Illness IndexBiomarkers

Identifiers

PMID20724311
PMCPMC3002765
OpenAlexW2154319559

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.