ArticleJournal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology2010
Fractures in myelomeningocele.
Article in Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Orthopedic management of myelomeningocele with a multidisciplinary approach: a systematic review of the literature.Journal of orthopaedic surgery and research · 2021Pooled it
- Is the handgrip pressure influenced by the same factors in typical children and adolescents and those with spina bifida?The journal of spinal cord medicine · 2026Article
- Analysis of Bone Mineral Density and Body Composition in Lower and Upper Limbs of Spina Bifida Patients Using DXA Scans.Progress in rehabilitation medicine · 2026Article
- Understanding Orthopaedic and Health-related Quality of Life Outcomes in Patients With Myelomeningocele Functional Classification 1 Spina Bifida in Relationship to Supportive Standing.Journal of the Pediatric Orthopaedic Society of North America · 2025Article
- Spina bifida and cardiorespiratory profile: the impact of leisure sport activities on physical fitness.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Article
- Independently ambulatory children with spina bifida experience near-typical knee and ankle joint moments and forces during walking.Gait & posture · 2023Article
- Quantitative Computed Tomography Assessment of Bone Deficits in Ambulatory Children and Adolescents with Spina Bifida: Importance of Puberty.JBMR plus · 2020Article
- Age-specific occurrence of pathological fractures in patients with spina bifida.European journal of pediatrics · 2020Article
- Article
- Spina bifida-predisposing heterozygous mutations in Planar Cell Polarity genes and Zic2 reduce bone mass in young mice.Scientific reports · 2018Article
- Fractures in spina bifida from childhood to young adulthood.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2017Article
- Quantitative Analysis of Lower Leg Adipose Tissue Distribution in Youth with Myelomeningocele.Journal of child neurology · 2016Article
- Bone mineral density in pediatric patients with meningomyelocele.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2016Article
- Risk of fracture prevention in spina bifida patients: correlation between bone mineral density, vitamin D, and electrolyte values.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2015Article
- Osteoporosis in paediatric patients with spina bifida.The journal of spinal cord medicine · 2012Review
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn patients with myelomeningocele (MMC), a high number of fractures occur in the paralyzed extremities, affecting mobility and independence. The aims of this retrospective cross-sectional study are to determine the frequency of fractures in our patient cohort and to identify trends and risk factors relevant for such fractures. MATERIALS AND
methodsBetween March 1988 and June 2005, 862 patients with MMC were treated at our hospital. The medical records, surgery reports, and X-rays from these patients were evaluated.
resultsDuring the study period, 11% of the patients (n = 92) suffered one or more fractures. Risk analysis showed that patients with MMC and thoracic-level paralysis had a sixfold higher risk of fracture compared with those with sacral-level paralysis. Femoral-neck z-scores measured by dual-energy X-ray absorptiometry (DEXA) differed significantly according to the level of neurological impairment, with lower z-scores in children with a higher level of lesion. Furthermore, the rate of epiphyseal separation increased noticeably after cast immobilization. Mainly patients who could walk relatively well were affected.
conclusionsPatients with thoracic-level paralysis represent a group with high fracture risk. According to these results, fracture and epiphyseal injury in patients with MMC should be treated by plaster immobilization. The duration of immobilization should be kept to a minimum (<4 weeks) because of increased risk of secondary fractures. Alternatively, patients with refractures can be treated by surgery, when nonoperative treatment has failed.
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