ArticleInternational journal of peptides2010
Ghrelin and functional dyspepsia.
Article in International journal of peptides, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01591174 (Evaluation of Liquid Gastric Emptying and Plasma Ghrelin in Children With Functional Dyspepsia), which is not on this map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluation of Liquid Gastric Emptying and Plasma Ghrelin in Children With Functional Dyspepsia
Who cites it
10 citing papers in PubMed, 25 citations in OpenAlex.
- Nigella sativa powder for helicobacter pylori infected patients: a randomized, double-blinded, placebo-controlled clinical trial.BMC complementary medicine and therapies · 2023Trial
- Current Concepts in Gastroparesis and Gastric Neuromuscular Disorders-Pathophysiology, Diagnosis, and Management.Diagnostics (Basel, Switzerland) · 2025Review
- Contribution of ghrelin to functional gastrointestinal disorders' pathogenesis.World journal of gastroenterology · 2019Review
- Comparative Researches of Semen Arecae and Charred Semen Arecae on Gastrointestinal Motility, Motilin, Substance P, and CCK in Chronically Stressed Rats.Evidence-based complementary and alternative medicine : eCAM · 2017Article
- Increase in plasma acyl ghrelin levels is associated with abatement of dyspepsia following Helicobacter pylori eradication.Journal of gastroenterology · 2016Article
- XiangshaLiujunzi decoction alleviates the symptoms of functional dyspepsia by regulating brain-gut axis and production of neuropeptides.BMC complementary and alternative medicine · 2015Article
- Changes in serum ghrelin level in relation to meal-time in patients with functional dyspepsia.United European gastroenterology journal · 2015Article
- What is the difference between Helicobacter pylori-associated dyspepsia and functional dyspepsia?Journal of neurogastroenterology and motility · 2011Article
- Update on ghrelin.International journal of peptides · 2010Article
- The effect of hydro-alcoholic extract ofAvicenna journal of phytomedicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The majority of patients with dyspepsia have no identifiable cause of their disease, leading to a diagnosis of functional dyspepsia (FD). While a number of different factors affect gut activity, components of the nervous and endocrine systems are essential for normal gut function. Communication between the brain and gut occurs via direct neural connections or endocrine signaling events. Ghrelin, a peptide produced by the stomach, affects gastric motility/emptying and secretion, suggesting it may play a pathophysiological role in FD. It is also possible that the functional abnormalities in FD may affect ghrelin production in the stomach. Plasma ghrelin levels are reported to be altered in FD, correlating with FD symptom score. Furthermore, some patients with FD suffer from anorexia with body-weight loss. As ghrelin increases gastric emptying and promotes feeding, ghrelin therapy may be a new approach to the treatment of FD.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.