ArticleOptics express2010
Dynamic ray tracing for modeling optical cell manipulation.
Article in Optics express, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Simulation and Experiment of the Trapping Trajectory for Janus Particles in Linearly Polarized Optical Traps.Micromachines · 2022Article
- Cell elongation via intrinsic antipodal stretching forces.Physical review. E, Statistical, nonlinear, and soft matter physics · 2012Article
- Erythrocyte deformation in high-throughput optical stretchers.Physical review. E, Statistical, nonlinear, and soft matter physics · 2012Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Current methods for predicting stress distribution on a cell surface due to optical trapping forces are based on a traditional ray optics scheme for fixed geometries. Cells are typically modeled as solid spheres as this facilitates optical force calculation. Under such applied forces however, real and non-rigid cells can deform, so assumptions inherent in traditional ray optics methods begin to break down. In this work, we implement a dynamic ray tracing technique to calculate the stress distribution on a deformable cell induced by optical trapping. Here, cells are modeled as three-dimensional elastic capsules with a discretized surface with associated hydrodynamic forces calculated using the Immersed Boundary Method. We use this approach to simulate the transient deformation of spherical, ellipsoidal and biconcave capsules due to external optical forces induced by a single diode bar optical trap for a range of optical powers.
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Registered trials
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